SILEVERTINIB
UNII RP9F537KVY

Substance Identification & Data

This profile provides standardized clinical and technical data for Silevertinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) RP9F537KVY.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2607829-38-7 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

RP9F537KVY

CAS Registry Number

2607829-38-7

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

SILEVERTINIB

Official standardized name for this substance within the FDA UNII nomenclature system.

InChIKey

C30H30ClFN6O2

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

LMOVDLRMIRLIJF-TUVXKDNKSA-N

Line notation for describing the chemical structure and connectivity of atoms.

NCI Thesaurus

C187115

National Cancer Institute reference terminology for clinical and research data.

PubChem CID

156071569

Unique identification number in the NCBI database of chemical substances.

INN ID

13382

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

OP-55

Identifier assigned by the United States Adopted Names Council.

Substance Type

chemical

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

C(#Cc1c(NC(/C=C/CN2CCOCC2)=O)cc3c(c1)ncnc3Nc4c(F)c(Cl)ccc4)[C@]56[C@](C5)(CN(C)C6)[H]

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Silevertinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

SILEVERTINIB

Common Names & Synonyms

EGFR-IN-76

SILEVERTINIB [INN]

SILEVERTINIB [USAN]

Systematic Nomenclature

(2E)-N-(4-((3-CHLORO-2-FLUOROPHENYL)AMINO)-7-(2-((1R,5S)-3-METHYL-3-AZABICYCLO(3.1.0)HEX-1-YL)ETHYNYL)-6-QUINAZOLINYL)-4-(4-MORPHOLINYL)-2-BUTENAMIDE

SYS

(E)-N-(4-((3-CHLORO-2-FLUOROPHENYL)AMINO)-7-(((1R,5S)-3-METHYL-3-AZABICYCLO(3.1.0)HEXAN-1-YL)ETHYNYL)QUINAZOLIN-6-YL)-4-MORPHOLINOBUT-2-ENAMIDE

SYS

-2-BUTENAMIDE, N-(4-((3-CHLORO-2-FLUOROPHENYL)AMINO)-7-(2-((1R,5S)-3-METHYL-3-AZABICYCLO(3.1.0)HEX-1-YL)ETHYNYL)-6-QUINAZOLINYL)-4-(4-MORPHOLINYL)-, (2E)-

SYS