LUMASIRAN
UNII RZT8C352O1

Substance Identification & Data

This profile provides standardized clinical and technical data for Lumasiran, uniquely identified by the FDA Unique Ingredient Identifier (UNII) RZT8C352O1.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1834610-13-7 and the RxNorm Concept ID (RxCUI) 2467140. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

RZT8C352O1

CAS Registry Number

1834610-13-7

RxNorm Concept ID

2467140

Detailed Substance Profile

Preferred Name

LUMASIRAN

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

RZT8C352O1

The specific atomic composition represented as a molecular structure string.

NCI Thesaurus

C170137

National Cancer Institute reference terminology for clinical and research data.

INN ID

10684

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

GH-49

Identifier assigned by the United States Adopted Names Council.

Substance Type

nucleicAcid

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Lumasiran. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

LUMASIRAN

Common Names & Synonyms

LUMASIRAN [INN]

LUMASIRAN [USAN]

LUMASIRAN [WHO-DD]

Systematic Nomenclature

RNA, (GM-SP-AM-SP-CM-UM-UM-UM-(2'-DEOXY-2'-FLUORO)C-AM-(2'-DEOXY-2'-FLUORO)U-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)C-UM-GM-GM-AM-AM-AM-UM-AM-UM-AM), 3'-(((2S,4R)-1-(29-((2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-14,14-BIS((3-((3-((5-((2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GALACTOPYRANOSYL)OXY)-1-OXOPENTYL)AMINO)PROPYL)AMINO)-3-OXOPROPOXY)METHYL)-1,12,19,25-TETRAOXO-16-OXA-13,20,24-TRIAZANONACOS-1-YL)-4-HYDROXY-2-PYRROLIDINYL)METHYL HYDROGEN PHOSPHATE), COMPLEX WITH RNA (UM-SP-(2'-DEOXY-2'-FLUORO)A-SP-UM-AM-UM-(2'-DEOXY-2'-FLUORO)U-UM-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)C-AM-GM-GM-AM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-AM-AM-GM-UM-CM-SP-CM-SP-AM) (1:1)

SYS