PEMLIMOGENE MEROLISBAC
UNII S2EGO8116S

Substance Identification & Data

This profile provides standardized clinical and technical data for Pemlimogene Merolisbac, uniquely identified by the FDA Unique Ingredient Identifier (UNII) S2EGO8116S.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
S2EGO8116S
CAS Registry Number
N/A
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
PEMLIMOGENE MEROLISBAC
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C124843
National Cancer Institute reference terminology for clinical and research data.
INN ID
10546
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
FG-96
Identifier assigned by the United States Adopted Names Council.
Substance Type
structurallyDiverse
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Pemlimogene Merolisbac. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

PEMLIMOGENE MEROLISBAC

Common Names & Synonyms

LADD LISTERIA MONOCYTOGENES JNJ-64041757
LIVE-ATTENUATED LISTERIA MONOCYTOGENES ENCODING EGFRVIII-MESOTHELIN VACCINE JNJ-64041757
PEMLIMOGENE MEROLISBAC [INN]
PEMLIMOGENE MEROLISBAC [USAN]
PEMLIMOGENE MEROLISBAC [WHO-DD]

Systematic Nomenclature

RECOMBINANT LIVE-ATTENUATED DOUBLE-DELETED (LADD) STRAIN OF LISTERIA MONOCYTOGENES (LM .DELTA.ACTA/.DELTA.INLB) EXPRESSING A FUSION PROTEIN COMPRISING THE N-TERMINAL 100 AMINO ACIDS OF THE LM ACTA PROTEIN (ACTAN100), 5 TANDEM COPIES OF A 21 AMINO ACID FRAGMENT OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III (EGFRVIII) AND AMINO ACIDS 35-622 OF HUMAN MESOTHELIN (MSLN), UNDER THE CONTROL THE LM ACTA (ACTIN-ASSEMBLY INDUCING PROTEIN PRECURSOR) PROMOTER, AND CONTAINED WITHIN AN EXPRESSION CASSETTE OF 3874 BP INSERTED AT THE LM TRNAARG LOCUS. BACTERIA GENETICALLY MODIFIED (ANTINEOPLASTIC)

Technical Codes

ADU-214
JNJ-64041757

External Clinical & Regulatory Resources

NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus