EFSERAKEFUSP ALFA
UNII S4NL6N7DWD

Substance Identification & Data

This profile provides standardized clinical and technical data for Efserakefusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) S4NL6N7DWD.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3082221-37-9 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
S4NL6N7DWD
CAS Registry Number
3082221-37-9
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
EFSERAKEFUSP ALFA
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C171385
National Cancer Institute reference terminology for clinical and research data.
INN ID
14103
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Efserakefusp Alfa
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Efserakefusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Efserakefusp Alfa

Common Names & Synonyms

IL-15 Super-agonist SHR1501
Interleukin-15 Agonist Fusion Protein SHR1501
Interleukin-15 receptor α chain [40-cysteine] (human sushi domain-containing fragment) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin G1 [5-serine] (human γ-1 chain hinge-CH2-CH3 fragment), disulfide with interleukin-15 [52-cysteine] (human), dimer
SHR-1501(human Fc fusion protein composed of the cytokine interleukin (IL)-15 cross-linked with the high-affinity binding sushi domain of IL-15 receptor alpha (IL-15Ra))
efserakefusp alfa [INN]
human interleukin-15 receptor subunit alpha (IL-15RA, IL-15R α, CD215; Uniprot: Q13261) sushi domain containing fragment (1-73), variant (S<sup>40</sup>>C), fused via peptide linker <sup>74</sup>GGGGSGGGGS<sup>83</sup> to a human immunoglobulin G1 (IgG1) Fc fragment (hinge-CH2-CH3-CHS domains) [Homo sapiens IGHG1*03 (hinge C<sup>88</sup>>S (84-98), CH2 (99-208), CH3 (209-313), CHS(314-315)) (84-315)], (40-52')-disulfide with human interleukin-15 (IL-15, Uniprot: P40933) (1'-114')), variant (L<sup>52'</sup>>C); dimer (94-94'', 97-97'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

Technical Codes

SHR-1501

External Clinical & Regulatory Resources

CAS
Common Chemistry
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NLM
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NCATS
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NIH
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