ZELECIMENT BASIVARSEN
UNII T7PH26YY2C
Substance Identification & Data
This profile provides standardized clinical and technical data for Zeleciment Basivarsen, uniquely identified by the FDA Unique Ingredient Identifier (UNII) T7PH26YY2C.
Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2767191-74-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.
T7PH26YY2C
2767191-74-0
N/A
Detailed Substance Profile
Preferred Name
ZELECIMENT BASIVARSEN
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
INN ID
12713
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
NO-127
Identifier assigned by the United States Adopted Names Council.
Substance Type
Zeleciment basivarsen
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Synonyms and Nomenclature
This section provides a complete list of nomenclature and identifier mappings for Zeleciment Basivarsen. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.
FDA Official Name
Zeleciment basivarsen
Common Names & Synonyms
Fab-G1 VH-CH1 chain (1-227) [VH Musmus/Homsap (Mus musculus IGHV3-6*01 (84.5%) -(IGHD) -IGHJ2*01 (85.7%)L124>V (115)/Homo sapiens IGHV4-30-4*01 (82.8%) -(IGHD) -IGHJ4*01 (85.7%) L123>T (114), CDR-IMGT [9.7.12] (26-34.52-58.97-108)) (1-119) -Homo sapiens IGHG1*01 CH1-h(100%), G1m17 CH1 K120 (CH1 K120 (216) (120-217), hinge 1-10 (218-227)) (120-217)], (222-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (85.3%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.51-53.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1(153), V101 (191) (108'-214') produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, non-glycosylated, substituted at N6 of 1 to 3 L-lysine residues with 1-{(5aRS,6SR,6aSR)-1-[(6S,9S)-1-amino-6-{[4-({[(6-{[all-P-ambo-2'-O,4'-C-methylene-P-thioadenylyl-(5'→3')-5-methyl-2'-O,4'-C-methylene-P-thiocytidylyl-(5'→3')-2'-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-(5'→3')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(5'→3')-2'-deoxy-P-thioadenylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thioadenylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thioguanylyl-(5'→3')-5-methyl-2'-O-(2-methoxyethyl)-P-thiocytidylyl-(5'→3')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(5'→3')-2'-O,4'-C-methylene-P-thioadenylyl-(5'→3')-5-methyl-2'-O,4'-C-methylene-5'-cytidylyl]oxy}hexyl)carbamoyl]oxy}methyl)pheny]carbamoyl}-1,8,11-trioxo-9-(propan-2-yl)-14,17,20-trioxa-2,7,10-triazadocosan-22-yl]-1,4,5,5a,6,6a,7,8-octahydrocyclopropa[5,6]cycloocta[1,2-d][1,2,3]triazol-6-yl}-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oyl (basivarsen) groups
Immunoglobulin G1 Fab fragment, anti-(human and Macaca fascicularis transferrin receptors type 1) (human-Mus musculus monoclonal F5298 γ1-chain), disulfide with human-Mus musculus monoclonal F5298 κ-chain, N6-amide with DNA d(P-thio)((2′-O,4′-C-methylene)m5rC-(2′-O,4′-C-methylene)rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rC-G-C-C-C-A-C-C-A-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rU-(2′-O,4′-C-methylene)m5rC-(2′-O,4′-C-methylene)rA) 5′-[6-[[[[4-[[N-[3-[2-[2-[2-[(5aS,6R,6aR)-6-(18-carboxy-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadec-1-yl)-1,4,5,5a,6,6a,7,8-octahydrocyclopropa[5,6]cycloocta[1,2-d]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethoxy]-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]hexyl hydrogen phosphate]
ZELECIMENT BASIVARSEN [USAN]
immunoglobulin Fab G1-kappa (VH-CH1_L-kappa), anti-[Homo sapiens TFRC (transferrin receptor, TfR1, TFR1, CD71)], monoclonal antibody; substituted at N6 of lysine residues with basivarsen groups
zeleciment basivarsen [INN]
Technical Codes
DYNE-101
immunoglobulin Fab G1-kappa (VH-CH1_L-kappa), anti-[Homo sapiens TFRC (transferrin receptor, TfR1, TFR1, CD71)], monoclonal antibody; substituted at N6 of lysine residues with basivarsen groups; Fab-G1 VH-CH1 heavy chain (1-227) [VH Musmus/Homsap (Mus musculus IGHV3-6*01 (84.5%) -(IGHD) -IGHJ2*01 (85.7%) L124>V (115)/Homo sapiens IGHV4-30-4*01 (82.8%) -(IGHD) -IGHJ4*01 (85.7%) L123>T (114), CDRIMGT [9.7.12] (26-34.52-58.97-108)) (1-119) -Homo sapiens IGHG1*01 (100%) CH1-h (100%), G1m17 CH1 K120 (CH1 K120 (216) (120-217), hinge 1-10 (218-227)) (120-227)], (222-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (85.3%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.51-53.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1(153), V101 (191) (108'-214')], produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, nonglycosylated; substituted at N6 of 1 to 3 L-lysine residues with 1-{(5aRS,6SR,6aSR)-1-[(6S,9S)-1-amino-6-{[4-({[(6-{[all-P-ambo-2'-O,4'-C-methylene-P-thioadenylyl-(5'→3')-5-methyl-2'-O,4'-C-methylene-P-thiocytidylyl-(5'→3')-2'-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-(5'→3')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(5'→3')-2'-deoxy-P-thioadenylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thioadenylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-Pthiocytidylyl-(5'→3')-2'-deoxy-P-thiocytidylyl-(5'→3')-2'-deoxy-P-thioguanylyl-(5'→3')-5-methyl-2'-O-(2-methoxyethyl)-P-thiocytidylyl-(5'→3')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(5'→3')-2'-O,4'-C-methylene-P-thioadenylyl-(5'→3')-5-methyl-2'-O,4'-C-methylene-5'-cytidylyl]oxy}hexyl)carbamoyl]oxy}methyl)pheny]carbamoyl} -1,8,11-trioxo-9-(propan-2-yl)-14,17,20-trioxa-2,7,10-triazadocosan-22-yl]-1,4,5,5a,6,6a,7,8-octahydrocyclopropa[5,6]cycloocta[1,2-d][1,2,3]triazol-6-yl}-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oyl (basivarsen) groups
