CRETOSTIMOGENE GRENADENOREPVEC
UNII THP9ML4NTZ

Substance Identification & Data

This profile provides standardized clinical and technical data for Cretostimogene Grenadenorepvec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) THP9ML4NTZ.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2414312-87-9 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

THP9ML4NTZ

CAS Registry Number

2414312-87-9

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

CRETOSTIMOGENE GRENADENOREPVEC

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C48412

National Cancer Institute reference terminology for clinical and research data.

INN ID

12143

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

HI-203

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Cretostimogene Grenadenorepvec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

CRETOSTIMOGENE GRENADENOREPVEC

Common Names & Synonyms

CG0070 GENOME STRUCTURE COMPRISES A LEFT ITR (5' ITR), A POLYA SEQUENCE, AN E2F RESPONSIVE PROMOTER LINKED TO THE ADENOVIRAL E1A CODING REGION, A HETEROLOGOUS CODING SEQUENCE ENCODING GM-CSF, AND A RIGHT ITR (3' ITR) AND CARRIES MOST OF THE WILD-TYPE HUMAN ADENOVIRUS AD5 GENOME (GENBANK: AY339865.1), EXCEPT FOR THE FOLLOWING REGIONS: (1) THE ENDOGENOUS PROMOTER OF THE ESSENTIAL EARLY GENE E1A HAS BEEN REPLACED BY HUMAN E2F-1 PROMOTER (GENBANK ACCESSION NO. AF516106.1), (2) A SV40 LATE POLYADENYLATION SIGNAL HAS BEEN PLACED UPSTREAM TO THE HE2F-1 PROMOTER, AND (3) E3 GP19KD-CODING REGION HAS BEEN REPLACED BY HUMAN GM-CSF CDNA SEQUENCE (ACCESSION NO. NM_000758.3)

CRETOSTIMOGENE GRENADENOREPVEC [INN]

CRETOSTIMOGENE GRENADENOREPVEC [USAN]

CRETOSTIMOGENE GRENADENOREPVEC [WHO-DD]