RINUMAFUSP ALFA
UNII UTJ6648D6D

Substance Identification & Data

This profile provides standardized clinical and technical data for Rinumafusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) UTJ6648D6D.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3059743-20-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
UTJ6648D6D
CAS Registry Number
3059743-20-0
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
RINUMAFUSP ALFA
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C226354
National Cancer Institute reference terminology for clinical and research data.
INN ID
13831
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Rinumafusp Alfa
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Rinumafusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Rinumafusp Alfa

Common Names & Synonyms

Immunoglobulin G1 [234-phenylalanine,239-alanine,434-alanine], anti-(human epidermal growth factor receptor HER3) (human monoclonal U3-1287 γ1-chain) fusion protein with peptide linker (GGGGS)2 fusion protein with 177-237-neuregulin 1 (human isoform β2 precursor), disulfide with human monoclonal U3-1287 κ-chain, dimer
human immunoglobulin G1-kappa anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)] fused at the C-terminus of each heavy chain via peptide linker (G 4S)2 to a fragment of human neuregulin 1 (NRG1, acetylcholine receptor-inducing activity protein (ARIA), breast cancer cell differentiation factor p45, glial growth factor, heregulin (HRG), Neu differentiation factor); gamma1 heavy chain (1-447) [VH (Homo sapiens IGHV4-34*01 -(IGHD) - IGHJ2*01, CDR-Kabat [5.16.9] (31-35.50-65.98-106)(1-117) -Homo sapiens IGHG1*03 (CH1 (118-215), hinge (216-230), CH2 L<sup>234</sup>>F, S<sup>239</sup>>A (231-340), CH3 N<sup>434</sup>>A (341-445), CHS (446-447)) (118-447)], fused via peptide linker <sup>448</sup>(GGGGS)<sub>2</sub><sup>457</sup> to human neuregulin 1 fragment (NRG1, acetylcholine receptor-inducing activity protein (ARIA), breast cancer cell differentiation factor p45, glial growth factor, heregulin (HRG), Neu differentiation factor) (177-237, 458-518 in the current sequence), disulfide with kappa light chain (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 -IGKJ1*01, CDR-Kabat [17.7.9] (24'-40'.56'-62'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (114'-220')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO), cell line CHO-K1, glycoform alfa
rinumafusp alfa [INN]

External Clinical & Regulatory Resources

CAS
Common Chemistry
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NLM
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NCATS
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