ZUNIBERGENE ROCPARVOVEC
UNII VFF5C4QV72

Substance Identification & Data

This profile provides standardized clinical and technical data for Zunibergene Rocparvovec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) VFF5C4QV72.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2856381-73-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
VFF5C4QV72
CAS Registry Number
2856381-73-0
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
ZUNIBERGENE ROCPARVOVEC
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C211814
National Cancer Institute reference terminology for clinical and research data.
INN ID
13246
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
structurallyDiverse
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Zunibergene Rocparvovec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ZUNIBERGENE ROCPARVOVEC

Common Names & Synonyms

ADENO-ASSOCIATED VIRUS VECTOR 4D-150
DNA (RECOMBINANT REPLICATION-DEFECTIVE ADENO-ASSOCIATED VIRUS VECTOR 4D-150 CYTOMEGALOVIRUS IMMEDIATE-EARLY ENHANCER ELEMENT PLUS CHICKEN .BETA.-ACTIN EXON 1 PLUS INTRON 1 PLUS VASCULAR ENDOTHELIAL GROWTH FACTOR C-SPECIFIC MICRORNA GENE PLUS CHICKEN .BETA.-ACTIN INTRON 1 FRAGMENT PLUS RABBIT .BETA.-GLOBIN SPLICE ACCEPTOR PLUS SYNTHETIC HUMAN VEGFR-1-VEGFR-2-IGG1-FC FUSION PROTEIN MONOMER PRECURSOR CODON-OPTIMIZED GENE PLUS SIMIAN VIRUS 40 POLYADENYLATION SIGNAL PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT FLANKS-SPECIFYING)
RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS (AAV) VECTOR WITH A RETINA-SPECIFIC CAPSID VARIANT, ENCODING A MICRORNA (MIRNA) TARGETING EXPRESSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR C (VEGF-C) AND A CODON-OPTIMISED FUSION PROTEIN THAT CONSISTS OF VEGF-BINDING REGIONS DERIVED FROM THE EXTRACELLULAR DOMAINS OF HUMAN VEGF RECEPTORS 1 AND 2 FUSED TO THE FC PORTION OF HUMAN IMMUNOGLOBULIN G1 (THE MATURE EXPRESSED PROTEIN IS EQUIVALENT TO AFLIBERCEPT), UNDER CONTROL OF A SYNTHETIC CAG PROMOTER AND THE SIMIAN VIRUS 40 POLYADENYLATION SEQUENCE, FLANKED BY AAV2 INVERTED TERMINAL REPEATS. THE VEGF-C TARGETING MIRNA SEQUENCE IS LOCATED WITHIN THE CHICKEN BETA-ACTIN INTRON OF THE CAG PROMOTER
ZUNIBERGENE ROCPARVOVEC [INN]

External Clinical & Regulatory Resources

CAS
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