IRPAGRATINIB
UNII X46B7JM4A8

Substance Identification & Data

This profile provides standardized clinical and technical data for Irpagratinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) X46B7JM4A8.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2230974-62-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
X46B7JM4A8
CAS Registry Number
2230974-62-4
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
IRPAGRATINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C28H32F2N6O5
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
PGRHEHZIRYNZDV-FUHWJXTLSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
C189047
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
135181440
Unique identification number in the NCBI database of chemical substances.
INN ID
12691
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
N(c1nc2c(nc(cc2cn1)-c3c(F)c(OC)cc(OC)c3F)N4CC(OC)(C)C4)[C@H]5[C@@H](NC(C=C)=O)CCOC5

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Irpagratinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

IRPAGRATINIB

Common Names & Synonyms

IRPAGRATINIB [INN]
IRPAGRATINIB [WHO-DD]

Systematic Nomenclature

2-PROPENAMIDE, N-((3S,4S)-3-((6-(2,6-DIFLUORO-3,5-DIMETHOXYPHENYL)-8-(3-METHOXY-3-METHYL-1-AZETIDINYL)PYRIDO(3,4-D)PYRIMIDIN-2-YL)AMINO)TETRAHYDRO-2H-PYRAN-4-YL)-
N-((3S,4S)-3-((6-(2,6-DIFLUORO-3,5-DIMETHOXYPHENYL)-8-(3-METHOXY-3-METHYL-1-AZETIDINYL)PYRIDO(3,4-D)PYRIMIDIN-2-YL)AMINO)TETRAHYDRO-2H-PYRAN-4-YL)-2-PROPENAMIDE

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus
NLM
PubChem Compound