FIROLIMOGENE AUTOTEMCEL
UNII XH2XT2GQS6

Substance Identification & Data

This profile provides standardized clinical and technical data for Firolimogene Autotemcel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) XH2XT2GQS6.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

XH2XT2GQS6

CAS Registry Number

N/A

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

FIROLIMOGENE AUTOTEMCEL

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C184824

National Cancer Institute reference terminology for clinical and research data.

INN ID

11551

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

ITIS TSN

180092

Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.

NCBI Taxonomy

9606

Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Firolimogene Autotemcel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

FIROLIMOGENE AUTOTEMCEL

Common Names & Synonyms

AUTOLOGOUS CD34+ CELLS ISOLATED FROM BONE MARROW OF NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY (X-SCID) PATIENTS, TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING CODON-OPTIMIZED HUMAN INTERLEUKIN-2 RECEPTOR SUBUNIT GAMMA (IL2RG) ALSO KNOWN AS COMMON GAMMA CHAIN (.GAMMA.C), DRIVEN BY A SHORT VERSION OF THE EF1.ALPHA. PROMOTER. THE VECTOR CONTAINS HUMAN IMMUNODEFICIENCY VIRUS (HIV) CENTRAL POLYPURINE TRACT SEQUENCES, THE HIV REV RESPONSE ELEMENT (RRE) AND IS FLANKED BY HIV LONG TERMINAL REPEATS. THE VECTOR ALSO CONTAINS A 400BP INSULATOR FRAGMENT FROM THE CHICKEN BETA-GLOBIN LOCUS INSERTED INTO THE DELETED U3 REGION OF THE HIV LONG TERMINAL REPEAT FOLLOWED BY A POLYADENYLATION SEQUENCE DERIVED FROM THE RABBIT BETA-GLOBIN GENE

FIROLIMOGENE AUTOTEMCEL [INN]

External Clinical & Regulatory Resources

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