VANGLUSAGENE ENSIPARVOVEC
UNII Y47XZ2EW2J

Substance Identification & Data

This profile provides standardized clinical and technical data for Vanglusagene Ensiparvovec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) Y47XZ2EW2J.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2382896-00-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

Y47XZ2EW2J

CAS Registry Number

2382896-00-4

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

VANGLUSAGENE ENSIPARVOVEC

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C180664

National Cancer Institute reference terminology for clinical and research data.

INN ID

11603

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

JK-90

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Vanglusagene Ensiparvovec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

VANGLUSAGENE ENSIPARVOVEC

Common Names & Synonyms

A RECOMBINANT LIVER-DIRECTED ADENO-ASSOCIATED VIRUS VECTOR EXPRESSING HUMAN ACID ALPHA-GLUCOSIDASE (GAA). A RECOMBINANT LIVER-DIRECTED ADENO-ASSOCIATED VIRUS SEROTYPE RH74 (AAVRH74) VECTOR THAT CONTAINS A BIOENGINEERED CAPSID DERIVED FROM AAVRH74 BY FOUR AMINO-ACID SUBSTITUTIONS AND A CODON-OPTIMIZED TRANSGENE EXPRESSION CASSETTE TO DRIVE HEPATIC SYNTHESIS AND SECRETION OF THE LYSOSOMAL ENZYME HUMAN ACID ALPHA-GLUCOSIDASE (GAA, .ALPHA.-1,4-GLUCOSIDASE, ACID MALTASE) VIA AN APOLIPOPROTEIN E HEPATIC CONTROL REGION 1 (APOE HCR1) ENHANCER/ HUMAN ALPHA 1-ANTITRYPSIN (HAAT) PROMOTER, A MODIFIED HUMAN BETA-GLOBIN INTRON 2 (HBB2) AND A BOVINE GROWTH HORMONE (BGH) POLYA SIGNAL SEQUENCE, FLANKED BY ADENO-ASSOCIATED VIRUS 2 (AAV2) INVERTED TERMINAL REPEATS (ITRS).

DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR AAV-SPARK100-GAA HUMAN LIVER-SPECIFIC EXPRESSION CASSETTE INCLUDING HUMAN LYSOSOMAL .ALPHA.-GLUCOSIDASE CODON-OPTIMIZED GENE GAA PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT FLANKS)

VANGLUSAGENE ENSIPARVOVEC [INN]

VANGLUSAGENE ENSIPARVOVEC [USAN]