POSNAFUSP ALFA
UNII YF3FFU3WCF

Substance Identification & Data

This profile provides standardized clinical and technical data for Posnafusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) YF3FFU3WCF.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2797073-53-9 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
YF3FFU3WCF
CAS Registry Number
2797073-53-9
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
POSNAFUSP ALFA
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C211829
National Cancer Institute reference terminology for clinical and research data.
INN ID
13119
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
protein
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Posnafusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

POSNAFUSP ALFA

Common Names & Synonyms

GAMMA 1 HEAVY FAB CHAIN (1-226) (VH (HOMO SAPIENS IGHV5-51*01 -(IGHD) -IGHJ4*01, CDR-KABAT (5.17.9) (31-35.50-66.99-107)) (1-118) -HOMO SAPIENS IGHG1*01 (CH1 (119-226)) FUSED VIA PEPTIDE LINKER 227 GGGGSGGGGSGGGGS 241 TO N-SULPHOGLUCOSAMINE SULPHOHYDROLASE (1-482, 242-723 IN THE CURRENT SEQUENCE), RESIDUE 291 POSTTRANSLATIONALLY MODIFIED TO FORMYLGLYCINE (FGLY), (221-219')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-219') (V-KAPPA (HOMO SAPIENS IGKV2D-29*02 -IGKJ1*01, CDR-KABAT (16.7.9) (24'-39'.55'-61'.94'-102')) (1'-112') -HOMO SAPIENS IGKC*01 (113'-219')); NON-COVALENT DIMER, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA
HUMANIZED IMMUNOGLOBULIN G1-KAPPA ANTIGEN-BINDING FRAGMENT (FAB), ANTI-(HUMAN TRANSFERRIN RECEPTOR 1 (HTFR, P90, CD71)) FUSED AT THE C-TERMINUS OF THE HEAVY CHAIN VIA A PEPTIDE LINKER TO HUMAN N-SULPHOGLUCOSAMINE SULPHOHYDROLASE (SGSH, SULFOGLUCOSAMINE SULFAMIDASE, SULPHAMIDASE, EC:3.10.1.1
IMMUNOGLOBULIN G1 FAB FRAGMENT, ANTI-(HUMAN TRANSFERRIN RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JR-441 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS)3 FUSION PROTEIN WITH HUMAN N-SULFOGLUCOSAMINE SULFOHYDROLASE, DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JR-441 .KAPPA.-CHAIN, DIMER
POSNAFUSP ALFA [INN]

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
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NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus