TUPARSTOBART
UNII Z0A08C63DF

Substance Identification & Data

This profile provides standardized clinical and technical data for Tuparstobart, uniquely identified by the FDA Unique Ingredient Identifier (UNII) Z0A08C63DF.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2649466-03-3 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

Z0A08C63DF

CAS Registry Number

2649466-03-3

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

TUPARSTOBART

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C157127

National Cancer Institute reference terminology for clinical and research data.

INN ID

12389

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

KL-190

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tuparstobart. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

TUPARSTOBART

Common Names & Synonyms

ANTI-LAG-3 MONOCLONAL ANTIBODY INCAGN02385

GAMMA1 HEAVY CHAIN HUMANIZED (1-450) (VH (HOMO SAPIENS IGHV1-46*02 (80.4%)-(IGHD) -IGHJ4*01 (100%), CDR-IMGT(8.8.14) (26-33.51-58.97-110)) (1-121)-HOMO SAPIENS IGHG1*03, G1M3, NG1M1, G1V29 CH2 A84.4 (CH1 R120 (218) (122-219), HINGE 1-15 (220-234), CH2 N84.4>A (301) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS K2>DEL (450))(122-450)), (224-215')-DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-215') (V-KAPPA (HOMO SAPIENS IGKV3-20*01 (86.5%) -IGKJ1*01 (91.7%), CDR-IMGT (7.3.9)(27-33.51-53.90-98)) (1'-108') -HOMO SAPIENS IGKC*01(100%), KM3 A45.1 (154), V101 (192) (109'-215')), DIMER (230-230'': 233-233'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1SV LACKING THE GLUTAMINE SYNTHETASE (GS-KO) GENE, NON-GLYCOSYLATED

IMMUNOGLOBULIN G1 (301-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN LYMPHOCYTE ACTIVATION GENE-3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL INCAGN02385 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL INCAGN02385 .KAPPA.-CHAIN, DIMER

IMMUNOGLOBULIN G1-KAPPA,ANTI-(HOMO SAPIENS LAG3 (LYMPHOCYTE ACTIVATING 3, LYMPHOCYTE-ACTIVATION 3, CD223)), HUMANIZED MONOCLONAL ANTIBODY

INCAGN 02385 [WHO-DD]

TUPARSTOBART [INN]

TUPARSTOBART [USAN]