ESONADOGENE IMVOPARVOVEC
UNII Z57CL8M2AE

Substance Identification & Data

This profile provides standardized clinical and technical data for Esonadogene Imvoparvovec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) Z57CL8M2AE.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2678565-23-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

Z57CL8M2AE

CAS Registry Number

2678565-23-4

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ESONADOGENE IMVOPARVOVEC

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C199044

National Cancer Institute reference terminology for clinical and research data.

INN ID

12424

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Esonadogene Imvoparvovec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ESONADOGENE IMVOPARVOVEC

Common Names & Synonyms

DNA (RECOMBINANT REPLICATION-DEFECTIVE ADENO-ASSOCIATED VIRUS 2 VECTOR NFS01 HUMAN CYTOMEGALOVIRUS ENHANCER PLUS HUMAN CYTOMEGALOVIRUS PROMOTER PLUS MACACINE HERPESVIRUS 3 CHIMERIC INTRON PLUS HUMAN HEME A FARNESYLTRANSFERASE GENE COX10 MITOCHONDRIAL TARGETING SIGNAL PEPTIDE FUSION WITH HUMAN MITOCHONDRIA NADH DEHYDROGENASE SUBUNIT 4 CODON-OPTIMIZED GENE PLUS HEME A FARNESYLTRANSFERASE GENE COX10 3'-UNTRANSLATED REGION PLUS SIMIAN VIRUS 40 POLYADENYLATION SIGNAL PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT FLANKS-SPECIFYING)

ESONADOGENE IMVOPARVOVEC [INN]

RECOMBINANT, NON-REPLICATING ADENO-ASSOCIATED VIRUS SEROTYPE 2 (AAV2) VECTOR ENCODING CODON-OPTIMISED HUMAN NADH DEHYDROGENASE SUBUNIT 4 (ALSO KNOWN AS NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; MTND4, NADH4, ND4) PRECEDED BY A KOZAK SEQUENCE AND A MITOCHONDRIAL TARGETING SEQUENCE FROM HUMAN HEME A: FARNESYLTRANSFERASE CYTOCHROME C OXIDASE ASSEMBLY FACTOR (ALSO KNOWN AS PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL; GENE COX10), UNDER CONTROL OF A HUMAN CYTOMEGALOVIRUS ENHANCER/PROMOTER PLUS A MACACINE HERPESVIRUS-3 CHIMERIC INTRON, FOLLOWED WITH A COX10 GENE 3'-UNTRANSLATED REGION (UTR), AND TERMINATED BY A SIMIAN VIRUS 40 (SV40) POLYADENYLATION SIGNAL, AND FLANKED BY AAV2 INVERTED TERMINAL REPEATS (ITRS)

External Clinical & Regulatory Resources

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