PETOSEMTAMAB
UNII Z6Z6IVE7W4

Substance Identification & Data

This profile provides standardized clinical and technical data for Petosemtamab, uniquely identified by the FDA Unique Ingredient Identifier (UNII) Z6Z6IVE7W4.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2213450-26-9 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

Z6Z6IVE7W4

CAS Registry Number

2213450-26-9

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

PETOSEMTAMAB

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C174952

National Cancer Institute reference terminology for clinical and research data.

INN ID

11136

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

KL-118

Identifier assigned by the United States Adopted Names Council.

Substance Type

Petosemtamab

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Petosemtamab. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Petosemtamab

Common Names & Synonyms

Immunoglobulin G1 [361-lysine, 376-lysine], anti-(human leucine-rich repeat-containing G protein-coupled receptor LGR5) (human monoclonal MCLA-158 γ1-chain), disulfide with human monoclonal MCLA-158 κ-chain, (236→229'), (239→232')-bis(disulfide) with immunoglobulin G1 [354-aspartic acid, 371-glutamic acid] anti-(human epidermal growth factor receptor) (human monoclonal MCLA-158 γ1-chain) disulfide with human monoclonal MCLA-158 κ-chain

PETOSEMTAMAB [USAN]

Petosemtamab [WHO-DD]

immunoglobulin G1-kappa, anti-[Homo sapiens EGFR (epidermal growth factor receptor, receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB)], and anti-[Homo sapiens LGR5 (leucine rich repeat containing G protein-coupled receptor 5, G protein-coupled receptor 49, GPR67, GPR49)], Homo sapiens monoclonal antibody, bispecific heterodimeric; gamma1 heavy chain Homo sapiens anti-EGFR (1-449) [VH (Homo sapiens IGHV7-4-1*02 (91.8%) -(IGHD) -IGHJ4*01 (93.3%)) [8.8.13] (1-120) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 (CH1 R120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 L7>D (354), E12 (359), M14 (361), L24>E (371) (344-448), CHS K2>del (449)) (121-449)], (223-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (100%) -IGKJ1*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108’-214’)]; gamma1 heavy chain Homo sapiens anti-LGR5 (1-456) [VH (Homo sapiens IGHV7-4-1*01 (92.9%) -(IGHD) -IGHJ4*01 (93.3%)) [8.8.20] (1-127) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 (CH1 R120 (224) (128-225), hinge 1-15 (226-240), CH2 (241-350), CH3 L7>K (361), E12 (366), M14 (368), T22>K (376) (351-455), CHS K2>del (456)) (128-456)], (230-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (100%) -IGKJ1*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108’-214’)]; dimer (229-236'':232-239'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO) cells, glycoform alfa

petosemtamab [INN]