INTISMERAN AUTOGENE
UNII ZG6U44T8SG

Substance Identification & Data

This profile provides standardized clinical and technical data for Intismeran Autogene, uniquely identified by the FDA Unique Ingredient Identifier (UNII) ZG6U44T8SG.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2931460-85-2 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
ZG6U44T8SG
CAS Registry Number
2931460-85-2
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
INTISMERAN AUTOGENE
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C146813
National Cancer Institute reference terminology for clinical and research data.
INN ID
13221
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
NO-164
Identifier assigned by the United States Adopted Names Council.
Substance Type
nucleicAcid
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Intismeran Autogene. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

INTISMERAN AUTOGENE

Common Names & Synonyms

INTISMERAN AUTOGENE [INN]
INTISMERAN AUTOGENE [USAN]
INTISMERAN AUTOGENE [WHO-DD]
MESSENGER RNA (MRNA), 5'-CAPPED, ENCODING A CODON-OPTIMIZED PATIENT SPECIFIC CONCATEMER OF UP TO 34 NEOANTIGENS DESIGNED SPECIFICALLY TO EACH INDIVIDUAL PATIENT'S TUMOR MUTANOME AND HUMAN LEUKOCYTE ANTIGEN (HLA) TYPE, FURTHER OPTIMIZED BY TWO ADDITIONAL STOP CODONS, FLANKED BY AN ARTIFICIAL 5' UNTRANSLATED REGION (UTR) AND A 3' UTR DERIVED FROM THE HUMAN HEMOGLOBIN SUBUNIT ALPHA (HBA1) GENE AND TERMINATED BY A 3' POLYADENYLATION (POLYA) TAIL; CONTAINS N1-METHYLPSEUDOURIDINE INSTEAD OF URIDINE (ALL-U>M1.PSI.)
RNA (RECOMBINANT 5'-(M7G-(5'->5')-PPP-GM)-CAPPED ALL URIDINE->N1-METHYLPSEUDOURIDINE-SUBSTITUTED PATIENT-SPECIFIC NEOANTIGEN-SPECIFYING PLUS 5'- AND 3'-UNTRANSLATED FLANKING REGION-CONTAINING POLY(A)-TAILED MESSENGER MRNA-4157), INNER SALT

Technical Codes

MRNA-4157

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus