NEGALSTOBART
UNII ZH12W2AA34

Substance Identification & Data

This profile provides standardized clinical and technical data for Negalstobart, uniquely identified by the FDA Unique Ingredient Identifier (UNII) ZH12W2AA34.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2360418-68-2 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

ZH12W2AA34

CAS Registry Number

2360418-68-2

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

NEGALSTOBART

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C168603

National Cancer Institute reference terminology for clinical and research data.

INN ID

12629

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Negalstobart. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

NEGALSTOBART

Common Names & Synonyms

GAMMA4 HEAVY CHAIN HOMO SAPIENS (1-446) (VH (HOMO SAPIENS IGHV4-39*01 (96.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT (10.7.12) (26-35.53-59.98-109)) (1-120)-HOMO SAPIENS IGHG4*01, NG4M(A) CH2 L92, G4V5 H P10, G4V4 CH2 A1.3, A1.2 (CH1 (121-218), HINGE 1-12 S10>P (228) (219-230), CH2 F1.3>A (234), L1.2>A (235), L92 (309) (231-340), CH3 (341-445), CHS K2>DEL (446)) (121-446)), (134-215')-DISULFIDE WITH KAPPA LIGHT CHAIN HOMO SAPIENS (1'-215') (V-KAPPA (HOMO SAPIENS IGKV1-33*01 (96.8%) -IGKJ4*01 (100%), CDR-IMGT(6.3.10) (27'-32'.50'-52'.89'-98')) (1'-108') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (154'), V101 (192') (109'-215')), DIMER (226-226'':229-229'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO)-K1SV CELL LINE LACKING THE GLUTAMINE SYNTHETASE GENE (GS-KO), GLYCOFORM ALFA

IBI-110

IMMUNOGLOBULIN G4 (228-PROLINE,234-ALANINE,235-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN LYMPHOCYTE ACTIVATION GENE-3) (HUMAN MONOCLONAL IBI110 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL IBI110 .KAPPA.-CHAIN, DIMER

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS LAG3 (LYMPHOCYTE ACTIVATING 3, LYMPHOCYTE-ACTIVATION 3, CD223)), HOMO SAPIENS MONOCLONAL ANTIBODY

NEGALSTOBART [INN]

NEGALSTOBART [WHO-DD]

RECOMBINANT HUMAN IGG4 KAPPA ANTI-LAG 3 MONOCLONAL ANTIBODY IBI110