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Active Ingredient Dactinomycin

Active Ingredient Details

What is Dactinomycin?

A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

What is the usage for Dactinomycin?

Dactinomycin is used to treat cancer. It works by slowing or stopping the growth of cancer cells.

How many products in the NDC database contain Dactinomycin?

The NDC database has 10 products with the active ingredient Dactinomycin. The following table lists all the products that have this active ingredient.

NDC Products with Dactinomycin

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
39822-2100Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousXgen Pharmaceuticals Djb, Inc.ACTIVE
42658-008Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousHisun Pharmaceuticals Usa, Inc.ACTIVE
55150-431Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousEugia Us LlcACTIVE
55150-928Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousAuromedics Pharma LlcACTIVE
55292-811Proprietary Name: Cosmegen DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousRecordati Rare Diseases, Inc.ACTIVE
58623-0098Proprietary Name: DactinomycinPowderZhejiang Hisun Pharmaceutical Co., Ltd.ACTIVE
66993-489Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousPrasco LaboratoriesACTIVE
68254-0017Proprietary Name: DactinomycinPowderConcord Biotech LimitedACTIVE
68305-200Proprietary Name: DactinomycinPowderSigma-aldrich CorporationACTIVE
71288-129Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousMeitheal Pharmaceuticals Inc.ACTIVE
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