Active Ingredient Dactinomycin
Active Ingredient Details
What is Dactinomycin?
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
What is the usage for Dactinomycin?
Dactinomycin is used to treat cancer. It works by slowing or stopping the growth of cancer cells.
How many products in the NDC database contain Dactinomycin?
The NDC database has 7 products with the active ingredient Dactinomycin. The following table lists all the products that have this active ingredient.
NDC Products with Dactinomycin
| NDC | Proprietary Name | Non-Proprietary Name | Dosage Form | Route Name | Company Name | Status | |
|---|---|---|---|---|---|---|---|
| 39822-2100 | Proprietary Name: Dactinomycin | Dactinomycin | Injection, Powder, Lyophilized, For Solution | Intravenous | Xgen Pharmaceuticals Djb, Inc. | ACTIVE | |
| 42658-008 | Proprietary Name: Dactinomycin | Dactinomycin | Injection, Powder, Lyophilized, For Solution | Intravenous | Hisun Pharmaceuticals Usa, Inc. | ACTIVE | |
| 55150-431 | Proprietary Name: Dactinomycin | Dactinomycin | Injection, Powder, Lyophilized, For Solution | Intravenous | Eugia Us Llc | ACTIVE | |
| 55150-928 | Proprietary Name: Dactinomycin | Dactinomycin | Injection, Powder, Lyophilized, For Solution | Intravenous | Eugia Us Llc | ACTIVE | |
| 58623-0098 | Proprietary Name: | Dactinomycin | Powder | Zhejiang Hisun Pharmaceutical Co., Ltd. | ACTIVE | ||
| 68254-0017 | Proprietary Name: | Dactinomycin | Powder | Concord Biotech Limited | ACTIVE | ||
| 71288-129 | Proprietary Name: Dactinomycin | Dactinomycin | Injection, Powder, Lyophilized, For Solution | Intravenous | Meitheal Pharmaceuticals Inc. | ACTIVE |
