NDC Active Ingredient Dactinomycin

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Active Ingredient Information

What is Dactinomycin?

A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

What is the usage for Dactinomycin?

Dactinomycin is used to treat cancer. It works by slowing or stopping the growth of cancer cells.

How many products in the NDC database contain Dactinomycin?

The NDC database has 7 products with the active ingredient Dactinomycin. The following table lists all the products that have this active ingredient.

NDC Products with Dactinomycin

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
39822-2100Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousXgen Pharmaceuticals Djb, Inc.ACTIVE
42658-008Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousHisun Pharmaceuticals Usa, Inc.ACTIVE
55150-431Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousAuromedics Pharma LlcACTIVE
55150-928Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousAuromedics Pharma LlcACTIVE
55292-811Proprietary Name: Cosmegen DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousRecordati Rare Diseases, Inc.ACTIVE
66993-489Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousPrasco LaboratoriesACTIVE
71288-129Proprietary Name: Dactinomycin DactinomycinInjection, Powder, Lyophilized, For SolutionIntravenousMeitheal Pharmaceuticals Inc.ACTIVE
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