Humulin Injection, Solution
Pricing Report NDC 0002-8824-27

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Humulin R U-500 Kwikpen (NDC 0002-8824-27) is $91.68261 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Eli Lilly And Company, this medication is distributed in a 2 SYRINGE in 1 CARTON / 3 mL in 1 SYRINGE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$91.68261
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
2 SYRINGE in 1 CARTON / 3 mL in 1 SYRINGE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2016, the NADAC wholesale price for (NDC ) has moved within a range of $85.76778 to $92.47053 per ML. Over this 9 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$85.7678 - $92.4705
Market Volatility
7.81% Variance
Latest Trend
0.05%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $91.68261 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $91.63819 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 22, 2026 $91.66333 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 18, 2026 $91.66351 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 18, 2026 $91.67603 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 21, 2026 $91.68177 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 17, 2025 $91.67554 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $91.68292 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $91.68839 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $91.68531 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $91.66497 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $91.68346 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $91.71003 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $91.69227 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 23, 2025 $91.72846 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 19, 2025 $91.74111 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 19, 2025 $91.72807 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 22, 2025 $91.72853 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 18, 2024 $91.74804 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $91.74920 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $91.76958 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $91.79143 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $91.81756 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $91.79612 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $91.76346 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $91.79165 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 17, 2024 $91.77485 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 19, 2023 $91.60672 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 19, 2023 $91.60672 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Sep 21, 2022 $91.88720 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 21, 2022 $91.88720 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 23, 2022 $91.78976 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 23, 2022 $91.78976 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 19, 2021 $91.85315 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 19, 2021 $91.85315 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Sep 23, 2020 $91.55455 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 23, 2020 $91.55455 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 20, 2019 $91.73566 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2019 $91.73566 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 23, 2019 $91.96021 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 23, 2019 $91.96021 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Mar 21, 2018 $92.00471 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 21, 2018 $92.00471 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 21, 2017 $92.19890 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 21, 2017 $92.19890 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 02, 2017 $92.47053 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 02, 2017 $92.47053 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Sep 21, 2016 $85.76778 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 21, 2016 $85.76778 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 17, 2016 $86.21614 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026