NDC Code 0025-1011-31
Package Description: 100 TABLET, FILM COATED in 1 BOTTLE
Price per Unit: $2.54924 per EA
Spironolactone and Hydrochlorothiazide
The combination of spironolactone and hydrochlorothiazide is used to treat high blood pressure. This medication is also used to treat patients with edema (fluid retention) caused by various conditions, including heart, liver, or kidney disease. Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine, but reduces the loss of potassium from the body. Hydrochlorothiazide is in a class of medications called diuretics (''water pills''). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Blood Pressure Medicines
What is high blood pressure?
High blood pressure, also called hypertension, is when blood puts too much pressure against the walls of your arteries. About 1 in 3 adults have high blood pressure, usually with no symptoms. But it can cause serious problems such as stroke, heart failure, heart attack, and kidney disease.
What lifestyle changes can help lower high blood pressure?
Healthy lifestyle changes can help reduce high blood pressure:
- Losing weight
- Being physically active
- Managing stress
- Reducing sodium in your diet
- Avoiding alcohol, tobacco, and illegal drugs
- Getting enough sleep
What if lifestyle changes alone cannot lower blood pressure?
Sometimes lifestyle changes alone cannot control or lower your high blood pressure. In that case, your health care provider may prescribe blood pressure medicines.
How do blood pressure medicines work?
Blood pressure medicines work in different ways to lower blood pressure:
- Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) keep your blood vessels from narrowing as much
- Calcium channel blockers prevent calcium from entering the muscle cells of your heart and blood vessels. This allows the blood vessels to relax.
- Diuretics remove extra water and sodium (salt) from your body. This lowers the amount of fluid in your blood. Diuretics are often used with other high blood pressure medicines, sometimes in one combined pill.
- Beta blockers help your heart beat slower and with less force. This means that your heart pumps less blood through your blood vessels. Beta blockers are typically used only as a backup option or if you also have certain other conditions.
Often, two or more medicines work better than one. While taking the medicines, it is still important to keep up with your healthy lifestyle changes.
NIH: National Heart, Lung, and Blood Institute
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