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Eplerenone is a medication used to treat high blood pressure and heart failure. It belongs to a class of drugs known as aldosterone receptor antagonists, which work by blocking the effects of aldosterone in the body. This leads to a reduction in sodium retention and therefore a decrease in blood pressure. Eplerenone is taken orally and is available as a tablet in various strengths. It is important to follow the dosing instructions provided by your doctor to ensure effective treatment and avoid potential side effects.*

This is a medical journal graph that shows the Hazard Ratios of All-Cause Mortality by Subgroups. The x-axis indicates the range of hazard ratios, and the y-axis shows the subgroups of patients based on their age, gender, race, diabetes, hypertension, Killip class, creatinine clearance, baseline beta-blockers, ACE inhibitors, digoxin, and diuretics. The hazard ratios are calculated as a ratio of the probability of death occurring in the group being studied versus the probability of death occurring in the control group. Unfortunately, the values and the significance level of the relationships displayed are not included in the text, so further interpretation is not-available.*

The text describes a figure showing the INSPRA dose response for reducing Trough Cuff SBP in Hypertension Studies. The figure includes the Placebo-Subtracted Adjusted Mean Change from Baseline in mmHg for #study1 QD, #study2 QD, and aStudy 2B1D. The x-axis shows varying dosages of INSPRA in mg/day (50, 100, 150, 200).*

The text describes a figure titled "INSPRA Dose Response - Trough Cuff DBP" showing the adjusted mean change in blood pressure from the baseline in hypertension studies. The figure represents the placebo-subtracted mean change for different doses of INSPRA. The doses are represented in milligrams per day on the X-axis and the mean change in blood pressure is represented on the Y-axis. There are three different studies (Study1, Study2, Study 25) represented by different symbols on the figure. No other information is available.*

This is a statement indicating that a particular product is distributed by G.D. Searle LLC, which is a division of Pfizer Inc, based in NY, NY with a zip code of 10017.*

INSPRA® (eplerenone) tablets in 25mg strength manufactured by D. Searle LLC, a division of Pfizer Inc. The lot area and expiration date of the product are provided on the packaging, but the output has some unreadable characters.*

INSPRA (eplerenone) is a medication available in tablet form and is meant for non-institutional use only. It comes in a unit dose package with 100 tablets and should not be used without medical supervision.*

This is a description of storage and usage information for INSPRA tablets containing eplerenone. The medication should be stored at 25°C with excursions allowed between 15-30°C, and should be kept in child-resistant containers. The tablets come in a 50mg strength, and prescribing information should be consulted for dosage and use. The product is distributed by G.D. Searle LLC, and the package includes 30 tablets.*