NDC 0046-0749 Premarin
Conjugated Estrogens Injection, Powder, Lyophilized, For Solution Intramuscular; Intraveno...
NDC Code 0046-0749-05
Package Description: 1 VIAL in 1 CARTON / 5 mL in 1 VIAL
What is NDC 0046-0749?
The NDC code 0046-0749 is assigned by the FDA to the product Premarin which is a human prescription drug product labeled by Wyeth Pharmaceuticals Llc, A Subsidiary Of Pfizer Inc.. The generic name of Premarin is conjugated estrogens. The product's dosage form is injection, powder, lyophilized, for solution and is administered via intramuscular; intravenous form. The product is distributed in a single package with assigned NDC code 0046-0749-05 1 vial in 1 carton / 5 ml in 1 vial. This page includes all the important details about this product, including active and inactive ingredients, pharmagologic classes, product uses and characteristics, UNII information and RxNorm crosswalk.
What are the uses for Premarin?
This medication is a female hormone. It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).
What are Premarin Active Ingredients?
An active ingredient is the substance responsible for the medicinal effects of a product specified by the substance's molecular structure or if the molecular structure is not known, defined by an unambiguous definition that identifies the substance. Each active ingredient name is the preferred term of the UNII code submitted.
- ESTROGENS, CONJUGATED 25 mg/5mL - A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.
Which are Premarin UNII Codes?
The UNII codes for the active ingredients in this product are:
- ESTROGENS, CONJUGATED (UNII: IU5QR144QX)
- ESTROGENS, CONJUGATED (UNII: IU5QR144QX) (Active Moiety)
Which are Premarin Inactive Ingredients UNII Codes?
The inactive ingredients are all the component of a medicinal product OTHER than the active ingredient(s). The acronym "UNII" stands for “Unique Ingredient Identifier” and is used to identify each inactive ingredient present in a product. The UNII codes for the inactive ingredients in this product are:
- LACTOSE MONOHYDRATE (UNII: EWQ57Q8I5X)
- SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)
What is the NDC to RxNorm Crosswalk for Premarin?
RxNorm is a normalized naming system for generic and branded drugs that assigns unique concept identifier(s) known as RxCUIs to NDC products.The NDC to RxNorm Crosswalk for this produdct indicates multiple concept unique identifiers (RXCUIs) are associated with this product:
- RxCUI: 211975 - Premarin Intravenous 25 MG Injection
- RxCUI: 211975 - estrogens, conjugated (USP) 25 MG Injection [Premarin]
- RxCUI: 310203 - estrogens, conjugated 25 MG Injection
- RxCUI: 310203 - estrogens, conjugated (USP) 25 MG Injection
Which are the Pharmacologic Classes for Premarin?
A pharmacologic class is a group of drugs that share the same scientifically documented properties. The following is a list of the reported pharmacologic class(es) corresponding to the active ingredients of this product.
* Please review the disclaimer below.
The estradiol cypionate and estradiol valerate forms of estrogen injection are used to treat hot flushes (hot flashes; sudden strong feelings of heat and sweating) and/or vaginal dryness, itching, and burning in women who are experiencing menopause (change of life; the end of monthly menstrual periods). However, women who need a medication only to treat vaginal dryness, itching, or burning should consider a different treatment. These forms of estrogen injection are also sometimes used to treat the symptoms of low estrogen in young women who do not produce enough estrogen naturally. The estradiol valerate form of estrogen injection is also sometimes used to relieve the symptoms of certain types of prostate (a male reproductive organ) cancer. The conjugated estrogens form of estrogen injection is used to treat abnormal vaginal bleeding that a doctor has decided is caused only by a problem with the amounts of certain hormones in the body. Estrogen injection is in a class of medications called hormones. It works by replacing estrogen that is normally produced by the body.
* Please review the disclaimer below.
We have moved the product label and warning information to a dedicated page, please follow the link below:View Product Label