Methadone Hydrochloride Concentrate
Pricing Report NDC 0054-3553-44

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Methadone Hydrochloride (NDC 0054-3553-44) is $0.55347 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Hikma Pharmaceuticals Usa Inc., this medication is distributed in a 1 BOTTLE in 1 CARTON / 30 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.55347
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE in 1 CARTON / 30 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jul 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.48572 to $0.75640 per ML. Over this 12 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.4857 - $0.7564
Market Volatility
55.73% Variance
Latest Trend
0.44%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.55347 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.55107 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.54987 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.54497 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.54367 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.54219 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.54072 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.53916 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.54150 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.53715 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.53356 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.52721 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.52824 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.54473 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.54142 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.54142 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.54142 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.54415 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.53211 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.54357 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.50804 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.48821 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.48654 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.48654 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.49793 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.48572 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.52545 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2016 $0.69217 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2016 $0.69217 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 22, 2016 $0.75567 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2016 $0.75567 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 23, 2016 $0.71067 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2016 $0.71067 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 17, 2016 $0.75640 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $0.68867 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $0.68867 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 21, 2015 $0.70461 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2014 $0.73087 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2014 $0.73087 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 19, 2014 $0.63607 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2014 $0.63607 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 22, 2014 $0.66900 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2014 $0.66900 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 18, 2013 $0.69053 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026