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The text provided contains information about the in vitro reduction factor [logso] for different production steps and the efficacy of these steps in reducing enveloped and non-enveloped viruses, specifically HIV-1 PRV SBV MEV PPV. Cold ethanol fractionation yielded reduction factors of 24.81, >6.28, >7.13, >7.13, and 2653 for enveloped viruses, while S/D treatment resulted in reduction factors of 2493, 523, 677 for non-enveloped viruses. pH4 treatment showed reduction factors of 24.33, 26.71, 6.71, 5.07, and L5 for enveloped viruses. Overall, the global reduction factor was >14.07, >18.22, 22061, >12.20, and >6.53 for the mentioned viruses.*