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Acyclovir Cream 5% is a medication to treat cold sores on the skin. Each gram of the cream contains 50 milligrams of acyclovir, along with other ingredients. It is only meant for cutaneous use and should be applied five times a day for four days. The medication is manufactured by Bausch Health Companies in Canada and distributed by Teva Pharmaceuticals in the US. It comes in a tube weighing 5.9 grams, and should be stored at or below 25°C. The prescribing information should be consulted for dosage information.*