Acetaminophen And Codeine Phosphate Solution
Pricing Report NDC 0121-0504-16

Latest NADAC: $0.42555 per ML · Effective Apr 23, 2025 · Est. package price $201.29 (473 ML)

Current Package Pricing Information

The latest wholesale acquisition cost for Acetaminophen And Codeine Phosphate (NDC 0121-0504-16) is $0.42555 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Apr 23, 2025.

As a a human prescription drug provided by Pai Holdings, Llc Dba Pai Pharma, this medication is distributed in a 473 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.42555
Per ML

Effective Date
Apr 23, 2025
Billable Units
473 ML
Estimated Package Price
$201.29
Data Status
As of Apr 30, 2025
C/I - Chain or Independent Pharmacy
Package NDC
Description
473 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.01163 to $0.43430 per ML. Over this 11 years and 5 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0116 - $0.4343
Market Volatility
3,634.31% Variance
Latest Trend
0.79%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Apr 23, 2025 $0.42555 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.42223 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.41550 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.40387 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.39439 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.38864 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.38869 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.39099 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.39565 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.39816 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.40591 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.40915 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026