Trihexyphenidyl Hydrochloride Solution
Pricing Report NDC 0121-0658-16

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Trihexyphenidyl Hydrochloride (NDC 0121-0658-16) is $0.07711 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Pai Holdings, Llc Dba Pai Pharma, this medication is distributed in a 473 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.07711
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
473 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.03078 to $0.07711 per ML. Over this 12 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0308 - $0.0771
Market Volatility
150.52% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.07711 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.07711 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.07223 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.06981 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.06792 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.06626 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.06690 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.06780 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.06916 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.06943 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.07040 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.07220 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.07249 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.07236 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.07148 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.07174 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.07199 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.06879 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.06670 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.06343 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.06287 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.06076 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.05990 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.05543 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.06537 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.06537 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 18, 2023 $0.06616 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.06616 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 21, 2023 $0.06234 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.06234 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 18, 2023 $0.06333 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.06333 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 21, 2022 $0.06908 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.06349 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.06349 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 22, 2020 $0.05955 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2019 $0.06190 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2019 $0.06190 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 19, 2019 $0.05386 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2019 $0.05386 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 20, 2016 $0.04487 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2016 $0.04487 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 23, 2016 $0.05904 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2015 $0.03659 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2015 $0.03659 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 22, 2015 $0.04824 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2015 $0.04824 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 18, 2015 $0.03831 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $0.03831 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 17, 2014 $0.03078 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2014 $0.03078 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 23, 2014 $0.03355 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2014 $0.03355 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 21, 2014 $0.03613 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2014 $0.03613 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 22, 2014 $0.04151 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2014 $0.04151 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 21, 2013 $0.03733 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2013 $0.03733 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026