Trihexyphenidyl Hydrochloride Solution
Pricing Report NDC 0121-0658-16

Current NADAC: $0.09773 per ML · Effective Aug 19, 2026

Current Package Pricing Information

The current wholesale acquisition cost for Trihexyphenidyl Hydrochloride (NDC 0121-0658-16) is $0.09773 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Pai Holdings, Llc Dba Pai Pharma, this medication is distributed in a 473 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.09773
Per ML

Effective Date
Aug 19, 2026
Data Status
As of Sep 09, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
473 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.03078 to $0.09796 per ML. Over this 12 years and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0308 - $0.0980
Market Volatility
218.26% Variance
Latest Trend
0.23%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $0.09773 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2026 $0.09796 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.07711 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.07711 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.07223 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.06981 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.06792 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.06626 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.06690 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.06780 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.06916 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.06943 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026