Lactulose Solution
Pricing Report NDC 0121-0873-08

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Lactulose (NDC 0121-0873-08) is $0.01762 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jul 23, 2025.

As a a human prescription drug provided by Pai Holdings, Llc Dba Pai Pharma, this medication is distributed in a 237 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.01762
Per ML

Effective Date
Jul 23, 2025
Billable Units
237 ML
Estimated Package Price
$4.18
Data Status
As of Jul 30, 2025
C/I - Chain or Independent Pharmacy
Package NDC
Description
237 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2020, the NADAC wholesale price for (NDC ) has moved within a range of $0.00836 to $0.02541 per ML. Over this 6 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0104 - $0.0254
Market Volatility
143.39% Variance
Latest Trend
4.86%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.02250 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.01952 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.02365 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.01892 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.02388 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.01853 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.02454 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.01909 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.02432 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.01873 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.02438 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.01853 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.02448 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.01803 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.02469 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.01675 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.02487 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.01675 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.02488 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.02541 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.01762 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.02539 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.01776 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.02533 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.01809 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.02461 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.01865 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.02462 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 16, 2025 $0.01809 MLC/I - Chain or Independent PharmacyCode 3, 5G - Generic
Apr 16, 2025 $0.01809 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 19, 2025 $0.01947 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.02458 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.01163 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.01974 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.02450 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.01382 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.01834 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.02420 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.01365 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.01662 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.02387 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.01398 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.01581 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.02404 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.01140 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.01548 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.02362 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.01306 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.01336 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.02335 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.01514 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.01170 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.01758 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.01274 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.01111 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.01195 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.00836 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.01082 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.01472 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.01205 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.01044 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.01370 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.00972 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.01157 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.00983 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.01332 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.01187 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.01240 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.01149 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.01283 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.01180 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.01261 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.01170 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.01230 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.01120 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.01271 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.01156 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.01231 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.01139 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.01316 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.01135 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.01252 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.01156 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.01338 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.01106 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.01231 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.01180 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.01511 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.01284 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.01479 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.01301 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.01509 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.01318 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.01566 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.01366 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.01534 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.01325 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.01560 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.01359 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.01662 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.01344 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.01514 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.01362 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.01637 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.01369 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.01654 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.01217 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.01612 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.01417 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.01605 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.01421 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.01495 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.01390 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.01519 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.01410 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.01591 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.01259 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.01471 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.01346 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.01483 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.01336 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.01501 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.01448 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.01494 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.01439 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.01452 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.01430 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.01465 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.01471 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.01366 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.01645 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.01441 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.01463 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 19, 2021 $0.01377 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 19, 2021 $0.01531 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 21, 2021 $0.01433 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 21, 2021 $0.01493 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 17, 2021 $0.01462 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 17, 2021 $0.01608 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 10, 2021 $0.01647 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 17, 2021 $0.01494 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2021 $0.01499 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 20, 2021 $0.01490 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 20, 2021 $0.01440 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $0.01453 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $0.01575 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $0.01451 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $0.01630 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $0.01467 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $0.01534 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $0.01499 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $0.01561 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.01446 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.01472 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $0.01487 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $0.01616 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2020 $0.01542 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2020 $0.01576 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2020 $0.01440 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2020 $0.01498 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $0.01528 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $0.01414 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 08, 2020 $0.01589 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 08, 2020 $0.01437 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026