Estradiol Valerate Injection
Pricing Report NDC 0143-9290-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Estradiol Valerate (NDC 0143-9290-01) is $20.90002 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Hikma Pharmaceuticals Usa Inc., this medication is distributed in a 1 VIAL in 1 CARTON / 5 mL in 1 VIAL configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$20.90002
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 VIAL in 1 CARTON / 5 mL in 1 VIAL
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jul 2021, the NADAC wholesale price for (NDC ) has moved within a range of $13.56783 to $24.04227 per ML. Over this 4 years and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$13.5678 - $24.0423
Market Volatility
77.20% Variance
Latest Trend
0.49%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $20.90002 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $21.00379 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $21.48967 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $22.37099 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $23.44422 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $22.53531 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $22.12627 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $21.27070 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $22.16703 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $21.98702 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $21.58747 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $21.18964 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $21.35186 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $21.37434 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $21.64092 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $22.30439 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $20.64950 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $17.81379 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $15.44163 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $13.77670 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $17.02339 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $19.62232 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $22.37991 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $13.56783 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $19.04774 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $13.84724 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $15.55177 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $21.46226 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $21.58982 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $23.19610 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $22.09586 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $19.50982 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $18.73817 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $21.35644 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $21.59671 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $21.26257 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $20.46533 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $19.88092 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $21.68125 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $22.74475 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $20.75467 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $21.51100 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $24.04227 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $21.48975 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $21.44055 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $21.00178 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $21.49527 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $21.49527 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 20, 2022 $19.70825 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $21.82620 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $19.65700 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $20.26314 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $20.60050 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $22.72933 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $22.72933 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 18, 2021 $21.77633 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $21.77633 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 07, 2021 $19.19800 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026