Daptomycin Injection, Powder, Lyophilized, For Solution
Pricing Report NDC 0143-9378-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Daptomycin (NDC 0143-9378-01) is $21.62494 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since May 21, 2025.

As a a human prescription drug provided by Hikma Pharmaceuticals Usa Inc., this medication is distributed in a 1 VIAL, SINGLE-DOSE in 1 CARTON / 10 mL in 1 VIAL, SINGLE-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$21.62494
Per EA

Effective Date
May 21, 2025
Billable Units
1 EA
Estimated Package Price
$21.62
Data Status
As of May 28, 2025
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 VIAL, SINGLE-DOSE in 1 CARTON / 10 mL in 1 VIAL, SINGLE-DOSE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $20.18648 to $28.39000 per EA. Over this 1 year and 1 month period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$20.1865 - $28.3900
Market Volatility
40.64% Variance
Latest Trend
7.13%
Date Unit Price Unit Source Method Rate
May 21, 2025 $21.62494 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $20.18648 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $20.30656 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $20.67959 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $21.98396 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $23.45540 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $23.87200 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $24.82889 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $27.07700 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $28.39000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $25.64857 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $24.84600 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $24.84600 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026