Methotrexate Solution
Pricing Report NDC 0143-9519-10

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Methotrexate (NDC 0143-9519-10) is $1.24307 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Hikma Pharmaceuticals Usa Inc., this medication is distributed in a 10 VIAL in 1 CARTON / 2 mL in 1 VIAL configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1.24307
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
10 VIAL in 1 CARTON / 2 mL in 1 VIAL
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2018, the NADAC wholesale price for (NDC ) has moved within a range of $1.15108 to $1.73143 per ML. Over this 8 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$1.1511 - $1.7314
Market Volatility
50.42% Variance
Latest Trend
0.82%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $1.24307 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $1.23294 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $1.21065 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $1.20603 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $1.23349 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $1.27340 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $1.32332 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $1.33320 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $1.34310 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $1.33081 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $1.32810 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $1.35238 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $1.38625 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $1.41373 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $1.40989 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $1.42581 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $1.44825 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $1.46891 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $1.42863 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $1.46419 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $1.34066 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $1.28753 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $1.26513 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $1.27655 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $1.28200 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $1.27643 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $1.27643 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $1.32225 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $1.32225 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 17, 2024 $1.15108 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $1.34971 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $1.34971 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 19, 2023 $1.35175 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $1.35175 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 25, 2018 $1.47295 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 18, 2018 $1.57700 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 20, 2018 $1.73143 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 23, 2018 $1.67000 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 18, 2018 $1.55417 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 11, 2018 $1.71750 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026