Alprazolam Tablet, Orally Disintegrating
Pricing Report NDC 0228-4022-11

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Alprazolam (NDC 0228-4022-11) is $1.17231 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Actavis Pharma, Inc., this medication is distributed in a 100 TABLET, ORALLY DISINTEGRATING in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1.17231
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$117.23
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET, ORALLY DISINTEGRATING in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.88650 to $1.37456 per EA. Over this 12 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.8865 - $1.3746
Market Volatility
55.05% Variance
Latest Trend
0.61%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $1.17231 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $1.16520 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $1.14565 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $1.14687 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $1.15576 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $1.22256 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $1.27269 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $1.32069 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $1.31384 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $1.31922 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $1.29306 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $1.25748 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $1.25805 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $1.28773 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $1.32753 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $1.32698 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $1.31808 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $1.26016 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $1.15652 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $1.15182 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $1.01556 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.98962 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.93592 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.88650 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $1.00879 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $1.03473 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $1.10654 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $1.11440 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $1.11440 EAC/I - Chain or Independent PharmacyCode 4G - Generic
May 20, 2020 $1.27292 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2020 $1.27292 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Apr 22, 2020 $1.33280 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2020 $1.29248 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2019 $1.16854 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2019 $1.16854 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Dec 19, 2018 $1.28974 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 19, 2018 $1.28974 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Aug 22, 2018 $1.23894 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 22, 2018 $1.23894 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Dec 20, 2017 $1.19333 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2017 $1.19333 EAC/I - Chain or Independent PharmacyCode 4G - Generic
May 17, 2017 $1.25387 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2017 $1.25387 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Sep 21, 2016 $1.30707 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 21, 2016 $1.30707 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Aug 17, 2016 $1.32270 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2016 $1.25606 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2016 $1.25606 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 20, 2016 $1.29498 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 20, 2016 $1.29498 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Oct 21, 2015 $1.37456 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 21, 2015 $1.37456 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Sep 23, 2015 $1.33342 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2015 $1.29540 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2015 $1.29540 EAC/I - Chain or Independent PharmacyCode 4G - Generic
May 20, 2015 $1.31922 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2015 $1.31922 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Apr 22, 2015 $1.32674 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2015 $1.35000 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2015 $1.35000 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Dec 17, 2014 $1.34668 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2014 $1.34668 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Nov 19, 2014 $1.29687 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2014 $1.34662 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2014 $1.34662 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jul 23, 2014 $1.31393 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2014 $1.31110 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2014 $1.32860 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2014 $1.31993 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2014 $1.33339 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2014 $1.30684 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2014 $1.29266 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 21, 2013 $1.32955 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 21, 2013 $1.32955 EAC/I - Chain or Independent PharmacyCode 4G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026