Tosymra Spray
Pricing Report NDC 0245-0812-61

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Tosymra (NDC 0245-0812-61) is $108.17958 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Upsher-smith Laboratories, Llc, this medication is distributed in a 6 BLISTER PACK in 1 CARTON / 1 BOTTLE, SPRAY in 1 BLISTER PACK (0245-0812-89) / .1 mL in 1 BOTTLE, SPRAY (0245-0812-59) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$108.17958
Per EA

Effective Date
Jun 17, 2026
Billable Units
1 EA
Estimated Package Price
$108.18
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
6 BLISTER PACK in 1 CARTON / 1 BOTTLE, SPRAY in 1 BLISTER PACK (0245-0812-89) / .1 mL in 1 BOTTLE, SPRAY (0245-0812-59)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $101.61287 to $108.78019 per EA. Over this 2 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$101.6129 - $108.7802
Market Volatility
7.05% Variance
Latest Trend
0.02%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $108.17958 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $108.15369 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 22, 2026 $108.15369 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 18, 2026 $107.92595 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 18, 2026 $107.81967 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 21, 2026 $107.81796 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 17, 2025 $107.63417 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $108.39320 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $108.39320 EAC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 18, 2025 $108.50592 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $108.50592 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 23, 2025 $108.53365 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 19, 2025 $108.53365 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 19, 2025 $108.78019 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 22, 2025 $108.78019 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 18, 2024 $108.76688 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $108.77167 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 01, 2024 $108.12614 EAC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2024 $108.12614 EAC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2024 $108.12614 EAC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 19, 2024 $101.62804 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $101.74333 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 17, 2024 $101.61287 EAC/I - Chain or Independent PharmacyCode 1, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026