Differin
Pricing Report NDC 0299-5915-45

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The latest wholesale acquisition cost for Differin (NDC 0299-5915-45) is $11.27062 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since May 21, 2025.

As a provided by Galderma Laboratories, L.p, this medication is distributed in a 1 TUBE in 1 CARTON / 45 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$11.27062
Per GM

Effective Date
May 21, 2025
Billable Units
45 GM
Estimated Package Price
$507.18
Data Status
As of May 13, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 TUBE in 1 CARTON / 45 g in 1 TUBE
Generic Benchmark
The generic equivalent rate is $2.56094 (Effective: Apr 22, 2026)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2013, the NADAC wholesale price for (NDC ) has moved within a range of $8.08642 to $11.56789 per GM. Over this 11 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$8.0864 - $11.5679
Market Volatility
43.05% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
May 21, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 23, 2025 $11.27062 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 17, 2022 $11.22365 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 17, 2022 $11.22365 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 17, 2022 $11.22365 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 17, 2022 $11.22365 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 17, 2022 $11.22365 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 17, 2021 $11.21791 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 23, 2020 $11.26984 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $11.27163 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 20, 2019 $11.25720 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2017 $11.21034 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 19, 2016 $11.29470 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 17, 2016 $11.56789 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 17, 2016 $11.56789 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 18, 2016 $11.27822 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 18, 2016 $11.27822 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 18, 2016 $11.27822 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Apr 01, 2016 $11.52552 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Apr 01, 2016 $11.52552 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2015 $10.48756 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2015 $9.53458 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 20, 2014 $8.66866 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 20, 2014 $8.66866 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 20, 2014 $8.66866 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 20, 2014 $8.66866 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 20, 2014 $8.66866 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2014 $8.49074 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2014 $8.49074 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
May 21, 2014 $8.08642 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2014 $8.08642 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 01, 2013 $8.22065 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 01, 2013 $8.22065 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 01, 2013 $8.22065 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 01, 2013 $8.22065 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 01, 2013 $8.22065 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 01, 2013 $8.22065 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026