Twyneo Cream
Pricing Report NDC 0299-5945-30

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Twyneo (NDC 0299-5945-30) is $31.65680 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 01, 2026.

As a a human prescription drug provided by Galderma Laboratories, L.p., this medication is distributed in a 1 BOTTLE, PUMP in 1 BOX / 30 g in 1 BOTTLE, PUMP configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$31.65680
Per GM

Effective Date
Aug 01, 2026
Billable Units
30 GM
Estimated Package Price
$949.70
Data Status
As of Aug 05, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE, PUMP in 1 BOX / 30 g in 1 BOTTLE, PUMP
Pricing Methodology Explanation
The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2022, the NADAC wholesale price for (NDC ) has moved within a range of $13.55478 to $31.65680 per GM. Over this 3 years and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$13.5548 - $31.6568
Market Volatility
133.55% Variance
Latest Trend
5.00%
Date Unit Price Unit Source Method Rate
Aug 01, 2026 $31.65680 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 22, 2026 $30.14934 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 17, 2026 $30.14934 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $30.04995 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 22, 2026 $30.01980 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $15.65742 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $15.65742 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 18, 2025 $15.65913 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $15.65913 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 23, 2022 $13.55478 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 23, 2022 $13.55478 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: August 05, 2026