Breztri Aerosol, Metered
Pricing Report NDC 0310-4616-39

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Breztri (NDC 0310-4616-39) is $61.44949 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Astrazeneca Pharmaceuticals Lp, this medication is distributed in a 28 AEROSOL, METERED in 1 INHALER configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$61.44949
Per GM

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
28 AEROSOL, METERED in 1 INHALER
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Dec 2020, the NADAC wholesale price for (NDC ) has moved within a range of $53.06078 to $61.44949 per GM. Over this 5 years and 5 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$53.0608 - $61.3082
Market Volatility
15.54% Variance
Latest Trend
0.01%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $61.30817 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 17, 2026 $61.44949 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $61.30272 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2026 $61.25613 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $61.25613 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2026 $61.25613 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2026 $61.16006 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $61.16006 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2026 $61.16006 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $59.47140 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 17, 2025 $59.37754 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $59.51093 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $59.29892 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $59.58233 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $59.24814 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $59.57245 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $59.34482 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $59.56244 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $59.40363 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $59.55138 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $59.21729 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $59.58053 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $59.58241 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2025 $59.55744 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2025 $59.55744 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2025 $59.55744 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2025 $59.49406 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2025 $59.49406 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2025 $59.49406 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2024 $57.82332 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 18, 2024 $57.76179 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $57.82374 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $57.76179 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $57.84035 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $57.87000 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $57.84924 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $57.94915 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $57.86767 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $57.95835 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $57.86269 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $57.95835 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $57.87034 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $57.95153 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $57.89167 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2024 $57.81841 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2024 $57.81841 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2024 $57.81841 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2024 $58.12660 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2024 $58.12660 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 18, 2023 $56.13438 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 18, 2023 $56.13438 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2023 $56.29164 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2023 $56.29164 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2023 $56.29164 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2023 $56.43359 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2023 $56.43359 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2022 $54.65261 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2022 $54.65261 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2022 $54.65261 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2022 $54.78990 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2022 $54.78990 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2022 $54.78990 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 22, 2021 $53.06078 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 22, 2021 $53.06078 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Mar 17, 2021 $53.19356 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 17, 2021 $53.19356 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 23, 2020 $53.06698 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 23, 2020 $53.06698 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026