Azelastine Hydrochloride And Fluticasone Propionate Spray, Metered
Pricing Report NDC 0378-3458-23

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Azelastine Hydrochloride And Fluticasone Propionate (NDC 0378-3458-23) is $2.32481 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Mylan Pharmaceuticals Inc., this medication is distributed in a 1 BOTTLE in 1 BOX / 120 SPRAY, METERED in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2.32481
Per GM

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE in 1 BOX / 120 SPRAY, METERED in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2020, the NADAC wholesale price for (NDC ) has moved within a range of $2.20148 to $6.68849 per GM. Over this 6 years period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.2015 - $6.6885
Market Volatility
203.82% Variance
Latest Trend
4.08%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $2.32481 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $2.23366 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $2.20148 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $2.25539 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $2.47956 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $2.64905 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $2.69944 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $2.83633 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $3.00755 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $3.18819 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $3.20319 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $3.26694 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $3.28163 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $3.28793 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $3.22203 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $3.19374 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $3.15474 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $3.11876 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $3.16645 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $3.06933 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $3.32273 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $3.29244 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $3.27421 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $2.98161 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $3.17270 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $2.99484 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $3.13424 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 20, 2024 $3.44092 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 21, 2024 $3.41270 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 17, 2024 $3.26049 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 20, 2023 $3.81253 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 22, 2023 $3.41875 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 18, 2023 $2.95379 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 20, 2023 $3.22727 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 23, 2023 $3.27793 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 19, 2023 $3.20736 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 21, 2023 $3.47516 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 17, 2023 $3.31252 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 19, 2023 $3.27966 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 22, 2023 $3.34324 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 22, 2023 $3.87398 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 18, 2023 $3.86104 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 21, 2022 $4.02504 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 23, 2022 $3.78014 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 19, 2022 $4.26574 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 21, 2022 $4.15775 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 17, 2022 $4.07456 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 20, 2022 $4.01882 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 22, 2022 $4.38739 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 18, 2022 $4.19496 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 20, 2022 $4.36450 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 23, 2022 $4.21868 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 23, 2022 $4.13934 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 19, 2022 $4.48111 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 22, 2021 $4.92890 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 17, 2021 $4.25038 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 20, 2021 $4.53014 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 22, 2021 $4.66372 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 18, 2021 $4.61221 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 21, 2021 $4.94237 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 23, 2021 $5.27303 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 19, 2021 $5.10463 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 21, 2021 $5.56370 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 17, 2021 $5.15526 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 17, 2021 $5.65989 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 20, 2021 $5.49421 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 23, 2020 $5.37846 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 18, 2020 $5.57843 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $6.38949 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 23, 2020 $6.24104 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 19, 2020 $6.14789 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 22, 2020 $6.54070 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 17, 2020 $6.50863 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 10, 2020 $6.68849 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026