Azelastine Hydrochloride And Fluticasone Propionate Spray, Metered
Pricing Report NDC 0378-3458-23

Current NADAC: $2.18679 per GM · Effective Aug 19, 2026
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Azelastine Hydrochloride And Fluticasone Propionate (NDC 0378-3458-23) is $2.18679 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Mylan Pharmaceuticals Inc., this medication is distributed in a 1 BOTTLE in 1 BOX / 120 SPRAY, METERED in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2.18679
Per GM

Pricing Unit
Per GM Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Aug 19, 2026
Data Status
As of Sep 09, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
0378-3458-23
Description
1 BOTTLE in 1 BOX / 120 SPRAY, METERED in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2020, the NADAC wholesale price for (NDC ) has moved within a range of $2.18679 to $6.68849 per GM. Over this 6 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.1868 - $6.6885
Market Volatility
205.86% Variance
Latest Trend
2.63%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $2.18679 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 22, 2026 $2.24581 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 17, 2026 $2.32481 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $2.23366 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $2.20148 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $2.25539 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $2.47956 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $2.64905 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $2.69944 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $2.83633 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $3.00755 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $3.18819 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026