Tretinoin Gel
Pricing Report NDC 0378-8086-15

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Tretinoin (NDC 0378-8086-15) is $3.66621 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Mylan Pharmaceuticals Inc., this medication is distributed in a 1 TUBE in 1 CARTON / 15 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$3.66621
Per GM

Effective Date
Jun 17, 2026
Billable Units
15 GM
Estimated Package Price
$54.99
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 TUBE in 1 CARTON / 15 g in 1 TUBE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Sep 2019, the NADAC wholesale price for (NDC ) has moved within a range of $1.72525 to $4.25457 per GM. Over this 6 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.2637 - $4.2546
Market Volatility
87.95% Variance
Latest Trend
1.19%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $3.66621 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 17, 2026 $2.58997 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $3.71019 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $2.57016 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $3.66541 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $2.51585 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $3.41007 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $2.47312 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $3.27595 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $2.46295 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $3.30739 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $2.52341 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $3.37956 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $2.53808 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $3.34615 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $2.47832 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $3.18310 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $2.39700 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $3.05556 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $2.39085 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $3.00673 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $2.42348 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $3.07958 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $2.46532 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $3.14241 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $2.48793 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $3.19577 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $2.47512 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $3.21364 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $2.42366 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $3.25191 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $2.31242 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $3.14255 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $2.12770 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $2.89121 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $1.90009 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $2.84249 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $2.09237 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $2.49288 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $1.76169 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $3.05257 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $2.70343 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $3.08651 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $2.38874 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $2.60207 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $2.24186 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $2.49090 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $1.72525 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $2.94558 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $2.38664 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $2.76392 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $1.97365 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $3.01692 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $1.75287 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 20, 2024 $3.65400 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 20, 2024 $2.62610 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 21, 2024 $3.53134 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 17, 2024 $3.74823 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 17, 2024 $2.62526 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 17, 2024 $2.62526 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 20, 2023 $3.64880 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 20, 2023 $2.48703 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 22, 2023 $2.26371 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 18, 2023 $3.43311 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 18, 2023 $3.43311 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 18, 2023 $2.74393 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 20, 2023 $3.24527 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 20, 2023 $2.77349 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 19, 2023 $3.68456 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 19, 2023 $3.68456 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jul 19, 2023 $2.70099 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 19, 2023 $2.70099 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jun 21, 2023 $2.37056 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 17, 2023 $3.71456 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 17, 2023 $3.71456 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
May 17, 2023 $2.81822 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 19, 2023 $3.24925 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 22, 2023 $3.88224 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 22, 2023 $2.54442 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 22, 2023 $2.54442 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Feb 22, 2023 $3.48911 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 22, 2023 $2.49809 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 18, 2023 $3.39819 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 18, 2023 $2.16633 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 21, 2022 $3.48222 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 23, 2022 $3.74567 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 23, 2022 $2.56717 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 23, 2022 $2.56717 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 19, 2022 $3.48593 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 19, 2022 $3.09726 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 21, 2022 $3.29587 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 21, 2022 $2.72128 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 17, 2022 $3.75450 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 17, 2022 $2.46107 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 20, 2022 $3.93771 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 20, 2022 $2.59394 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 22, 2022 $2.49959 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 18, 2022 $3.72643 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 18, 2022 $3.72643 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
May 18, 2022 $2.25111 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 23, 2022 $3.76373 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 23, 2022 $3.76373 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Mar 23, 2022 $2.81852 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 23, 2022 $2.81852 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Feb 23, 2022 $3.89120 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 23, 2022 $2.65189 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 19, 2022 $3.51052 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 19, 2022 $2.49428 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 22, 2021 $3.69829 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 17, 2021 $3.28387 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 20, 2021 $3.77486 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 22, 2021 $3.61611 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 18, 2021 $3.55080 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 21, 2021 $4.16342 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 23, 2021 $4.01033 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 23, 2021 $2.46581 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 23, 2021 $2.46581 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
May 19, 2021 $4.25457 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 17, 2021 $2.65203 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 17, 2021 $2.65203 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Feb 17, 2021 $3.83845 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 17, 2021 $3.83845 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jan 20, 2021 $4.08793 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 23, 2020 $3.34289 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 18, 2020 $4.22622 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $4.12600 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $2.53087 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 21, 2020 $2.53087 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Aug 19, 2020 $4.09034 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 19, 2020 $4.09034 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jul 22, 2020 $3.14609 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 22, 2020 $3.14609 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jun 17, 2020 $2.67725 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2020 $3.37844 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2020 $4.10875 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2020 $4.10875 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Apr 22, 2020 $3.38409 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2020 $3.29352 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2020 $4.08149 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2020 $4.08149 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Feb 19, 2020 $2.97719 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2020 $4.15920 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2020 $2.78317 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2019 $4.05760 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2019 $3.36287 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2019 $2.81232 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2019 $2.81232 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 23, 2019 $3.83340 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 09, 2019 $3.33916 GMC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Sep 18, 2019 $3.97391 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 04, 2019 $3.97175 GMC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026