Daptomycin Injection, Powder, Lyophilized, For Solution
Pricing Report NDC 0409-0122-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Daptomycin (NDC 0409-0122-01) is $20.76857 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 21, 2026.

As a a human prescription drug provided by Hospira, Inc., this medication is distributed in a 1 VIAL, SINGLE-DOSE in 1 CARTON / 10 mL in 1 VIAL, SINGLE-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$20.76857
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Jan 21, 2026
Billable Units
1 EA
Estimated Package Price
$20.77
Data Status
As of Jan 21, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
0409-0122-01
Description
1 VIAL, SINGLE-DOSE in 1 CARTON / 10 mL in 1 VIAL, SINGLE-DOSE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $20.10200 to $28.39000 per EA. Over this 1 year and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$20.1020 - $28.3900
Market Volatility
41.23% Variance
Latest Trend
1.63%
Date Unit Price Unit Source Method Rate
Jan 21, 2026 $20.76857 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $20.43529 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $20.10200 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $20.10200 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $24.27429 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $24.27429 EAC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Jun 18, 2025 $22.16429 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $21.62494 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $20.18648 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $20.30656 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $20.67959 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $21.98396 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $23.45540 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $23.87200 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $24.82889 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $27.07700 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $28.39000 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $25.64857 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $24.84600 EAC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $24.84600 EAC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026