Naloxone Hydrochloride Injection, Solution
Pricing Report NDC 0409-1215-01

Current NADAC: $4.01468 per ML · Effective Aug 19, 2026

Current Package Pricing Information

The current wholesale acquisition cost for Naloxone Hydrochloride (NDC 0409-1215-01) is $4.01468 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Hospira, Inc., this medication is distributed in a 10 VIAL, SINGLE-DOSE in 1 CARTON / 1 mL in 1 VIAL, SINGLE-DOSE (0409-1215-21) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$4.01468
Per ML

Effective Date
Aug 19, 2026
Data Status
As of Sep 09, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
10 VIAL, SINGLE-DOSE in 1 CARTON / 1 mL in 1 VIAL, SINGLE-DOSE (0409-1215-21)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Dec 2015, the NADAC wholesale price for (NDC ) has moved within a range of $3.81717 to $15.78388 per ML. Over this 10 years and 7 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$3.8172 - $15.7839
Market Volatility
313.50% Variance
Latest Trend
5.05%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $4.01468 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2026 $4.22833 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $4.41350 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $4.37712 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $4.25868 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $4.08955 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $3.95157 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $3.84465 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $3.81717 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $3.86703 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $4.18946 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $4.81880 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026