Acetylcysteine Solution
Pricing Report NDC 0409-3307-03

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Acetylcysteine (NDC 0409-3307-03) is $0.63904 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Hospira, Inc., this medication is distributed in a 3 VIAL in 1 CARTON / 30 mL in 1 VIAL (0409-3307-11) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.63904
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
3 VIAL in 1 CARTON / 30 mL in 1 VIAL (0409-3307-11)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jan 2014, the NADAC wholesale price for (NDC ) has moved within a range of $0.23013 to $0.64481 per ML. Over this 12 years and 4 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.2301 - $0.6448
Market Volatility
180.19% Variance
Latest Trend
0.30%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.63904 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.64099 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.64167 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.64297 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.64481 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.61705 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.57748 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.54064 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.53357 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.53710 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.53234 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.52581 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.51794 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.51184 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.49833 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.48343 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.47357 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.52242 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.57667 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.57667 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.57667 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.62804 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.62804 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 20, 2022 $0.38115 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.38115 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 19, 2021 $0.44878 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 19, 2021 $0.44878 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 21, 2020 $0.35000 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $0.35000 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 19, 2020 $0.33289 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.33289 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 20, 2020 $0.35489 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2020 $0.35489 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 17, 2016 $0.31580 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2016 $0.31580 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 20, 2016 $0.32116 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2016 $0.32070 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2016 $0.32070 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 20, 2016 $0.32096 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2016 $0.30319 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2016 $0.30319 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 23, 2015 $0.30806 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2015 $0.30806 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 18, 2015 $0.30860 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2015 $0.30905 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2015 $0.30905 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 22, 2015 $0.30900 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2015 $0.30661 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2015 $0.30489 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $0.26220 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $0.26220 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 17, 2014 $0.25922 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2014 $0.25922 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 23, 2014 $0.25524 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2014 $0.25524 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 22, 2014 $0.23013 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2014 $0.23013 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026