Vancomycin Hydrochloride Injection, Powder, Lyophilized, For Solution
Pricing Report NDC 0409-6509-49

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Vancomycin Hydrochloride (NDC 0409-6509-49) is $39.31600 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 18, 2024.

As a a human prescription drug provided by Hospira, Inc., this medication is distributed in a 1 VIAL, PHARMACY BULK PACKAGE in 1 CARTON / 100 mL in 1 VIAL, PHARMACY BULK PACKAGE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$39.31600
Per EA

Effective Date
Sep 18, 2024
Billable Units
1 EA
Estimated Package Price
$39.32
Data Status
As of Sep 10, 2025
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 VIAL, PHARMACY BULK PACKAGE in 1 CARTON / 100 mL in 1 VIAL, PHARMACY BULK PACKAGE
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $17.50800 to $46.28714 per EA. Over this 10 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$17.5080 - $46.2871
Market Volatility
164.38% Variance
Latest Trend
38.91%
Date Unit Price Unit Source Method Rate
Sep 18, 2024 $39.31600 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $39.31600 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 18, 2024 $39.31600 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $39.31600 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 20, 2017 $28.30333 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2017 $28.30333 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 21, 2016 $29.51167 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2016 $29.51167 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 20, 2016 $20.53000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2016 $20.53000 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 22, 2016 $23.96500 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2016 $27.23714 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2016 $27.23714 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 20, 2016 $27.23714 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2016 $27.23714 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 23, 2015 $32.80667 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2015 $32.80667 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 23, 2015 $32.80667 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2015 $32.80667 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 19, 2015 $17.50800 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2015 $17.50800 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 19, 2015 $17.50800 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2015 $17.50800 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 18, 2015 $26.66600 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2015 $26.66600 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 18, 2015 $26.66600 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2015 $26.66600 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 18, 2015 $46.28714 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2015 $46.28714 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2015 $24.56000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2015 $24.56000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2014 $25.84000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2014 $25.84000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2014 $20.83000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2014 $20.83000 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2014 $17.79200 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2014 $17.79200 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2014 $20.97667 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2014 $20.97667 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 18, 2014 $20.97667 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2014 $20.97667 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 21, 2014 $26.52125 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2014 $26.52125 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2014 $21.66200 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2014 $21.66200 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 19, 2014 $21.66200 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2014 $21.66200 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 22, 2014 $24.08333 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2014 $24.08333 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2013 $26.87667 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2013 $26.87667 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 21, 2013 $26.87667 EAC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2013 $26.87667 EAC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026