Vancomycin Hydrochloride Injection, Powder, Lyophilized, For Solution
Pricing Report NDC 0409-6533-21
View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Current Package Pricing Information
The latest wholesale acquisition cost for Vancomycin Hydrochloride (NDC 0409-6533-21) is $2.95907 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Mar 19, 2025.
As a a human prescription drug provided by Hospira, Inc., this medication is distributed in a 10 VIAL in 1 CARTON / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL (0409-6533-11) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $2.95907 Per EA
Pricing Unit
Effective Date
Mar 19, 2025
Billable Units
10 EA
Estimated Package Price
$29.59
Data Status
As of Apr 16, 2025
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Nov 2013, the NADAC wholesale price for (NDC ) has moved within a range of $2.53680 to $13.24200 per EA. Over this 11 years and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$2.5368 - $13.2420
$2.5368 - $13.2420
Market Volatility
422.00% Variance
422.00% Variance
Latest Trend
0.26%
0.26%
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Mar 19, 2025 | $2.95907 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 19, 2025 | $2.95907 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2025 | $2.96691 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2025 | $2.96691 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 22, 2025 | $2.84132 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 22, 2025 | $2.84132 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2024 | $2.75444 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2024 | $2.75444 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 20, 2024 | $2.53680 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 20, 2024 | $2.53680 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2024 | $2.56117 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2024 | $2.56117 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Sep 18, 2024 | $2.56117 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2024 | $2.56117 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Aug 21, 2024 | $3.07186 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 21, 2024 | $3.07186 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 17, 2024 | $3.04433 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 17, 2024 | $3.04433 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 19, 2024 | $3.38633 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 19, 2024 | $3.38633 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 22, 2024 | $3.38633 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 22, 2024 | $3.38633 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 17, 2024 | $3.12275 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 17, 2024 | $3.12275 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2020 | $8.78880 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2020 | $8.78880 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Sep 18, 2019 | $5.52571 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2019 | $5.52571 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Dec 19, 2018 | $4.73660 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 19, 2018 | $4.73660 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Oct 17, 2018 | $4.97980 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 17, 2018 | $4.97980 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Sep 19, 2018 | $6.26300 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 18, 2018 | $4.65100 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 18, 2018 | $4.65100 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Mar 21, 2018 | $5.41760 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 21, 2018 | $5.41760 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Feb 21, 2018 | $12.41900 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 20, 2017 | $8.67770 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 20, 2017 | $8.67770 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Aug 23, 2017 | $13.18640 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 19, 2017 | $13.08814 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 17, 2017 | $13.24200 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 17, 2017 | $13.24200 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Feb 22, 2017 | $12.93014 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 22, 2017 | $12.93014 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Jan 18, 2017 | $9.24229 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 23, 2016 | $11.01286 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 23, 2016 | $11.01286 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Aug 17, 2016 | $9.62640 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 17, 2016 | $9.62640 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Jul 20, 2016 | $6.51456 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 22, 2016 | $5.00350 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 18, 2016 | $5.18875 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 20, 2016 | $6.31200 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 23, 2016 | $6.60210 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 17, 2016 | $5.43480 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 23, 2015 | $6.67478 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 23, 2015 | $6.67478 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Nov 18, 2015 | $5.71373 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 18, 2015 | $7.47490 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 18, 2015 | $7.47490 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Feb 18, 2015 | $8.26920 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 21, 2015 | $5.08743 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 17, 2014 | $5.32341 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 19, 2014 | $3.59555 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 22, 2014 | $3.66092 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 17, 2014 | $4.14907 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 20, 2014 | $4.01044 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 23, 2014 | $4.11190 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 18, 2014 | $4.25700 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 21, 2014 | $4.15891 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 23, 2014 | $3.79213 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2014 | $3.85463 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2014 | $3.85463 | EA | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Jan 22, 2014 | $4.19580 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2013 | $4.21336 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 21, 2013 | $3.56407 | EA | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: June 17, 2026
