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  5. NDC Package Code: 0409-6581-01 Marcaine With Epinephrine

NDC Package 0409-6581-01 Marcaine With Epinephrine

Bupivacaine Hydrochloride And Epinephrine Injection, Solution Perineural - View Billable Units, 11-Digit Format, RxNorm

Table of Contents

    1. Package Information
    2. Frequently Asked Questions

Package Information

Find all the important details about this NDC Package code, including the 11-Digit NDC Billing number, billing units, wholesale price, RxNorm crosswalk, active ingredients, pharmacologic clasess, etc.

NDC Package Code:
0409-6581-01
Package Description:
1 VIAL, MULTI-DOSE in 1 CARTON / 50 mL in 1 VIAL, MULTI-DOSE
Product Code:
0409-6581
Proprietary Name:
Marcaine With Epinephrine
Non-Proprietary Name:
Bupivacaine Hydrochloride And Epinephrine
Substance Name:
Bupivacaine Hydrochloride; Epinephrine Bitartrate
Usage Information:
MARCAINE / MARCAINE WITH EPINEPHRINE is indicated in adults for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. Specific concentrations and presentations of MARCAINE / MARCAINE WITH EPINEPHRINE are recommended for each type of block indicated to produce local or regional anesthesia or analgesia [see Dosage and Administration (2.2)].
11-Digit NDC Billing Format:
00409658101
Billing Unit:
ML - Billing unit of "milliliter" is used when a product is measured by its liquid volume.
NDC to RxNorm Crosswalk:
  • RxCUI: 1012377 - BUPivacaine HCl 0.25 % / EPINEPHrine 1:200,000 Injectable Solution
  • RxCUI: 1012377 - bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML Injectable Solution
  • RxCUI: 1012377 - bupivacaine hydrochloride 0.25 % / epinephrine (as epinephrine bitartrate) 1:200,000 Injectable Solution
  • RxCUI: 1012381 - Marcaine 0.25 % / EPINEPHrine 1:200,000 Injectable Solution
  • RxCUI: 1012381 - bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML Injectable Solution [Marcaine with Epinephrine]
    • Product Type:
    Human Prescription Drug
    Labeler Name:
    Hospira, Inc.
    Dosage Form:
    Injection, Solution - A liquid preparation containing one or more drug substances dissolved in a suitable solvent or mixture of mutually miscible solvents that is suitable for injection.
    Administration Route(s):
  • Perineural - Administration surrounding a nerve or nerves.
    • Active Ingredient(s):
  • BUPIVACAINE HYDROCHLORIDE 5 mg/mL
  • EPINEPHRINE BITARTRATE .0091 mg/mL
    • Pharmacologic Class(es):
  • Adrenergic alpha-Agonists - [MoA] (Mechanism of Action)
  • Adrenergic beta-Agonists - [MoA] (Mechanism of Action)
  • Amide Local Anesthetic - [EPC] (Established Pharmacologic Class)
  • Amides - [CS]
  • Catecholamine - [EPC] (Established Pharmacologic Class)
  • Catecholamines - [CS]
  • Local Anesthesia - [PE] (Physiologic Effect)
  • alpha-Adrenergic Agonist - [EPC] (Established Pharmacologic Class)
  • beta-Adrenergic Agonist - [EPC] (Established Pharmacologic Class)
    • Sample Package:
    No
    FDA Application Number:
    NDA016964
    Marketing Category:
    NDA - A product marketed under an approved New Drug Application.
    Start Marketing Date:
    09-26-2022
    Listing Expiration Date:
    12-31-2025
    Exclude Flag:
    N
    Code Structure:

    The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

    * Please review the disclaimer below.

    Frequently Asked Questions

    What is NDC 0409-6581-01?

    The NDC Packaged Code 0409-6581-01 is assigned to a package of 1 vial, multi-dose in 1 carton / 50 ml in 1 vial, multi-dose of Marcaine With Epinephrine, a human prescription drug labeled by Hospira, Inc.. The product's dosage form is injection, solution and is administered via perineural form.

    Is NDC 0409-6581 included in the NDC Directory?

    Yes, Marcaine With Epinephrine with product code 0409-6581 is active and included in the NDC Directory. The product was first marketed by Hospira, Inc. on September 26, 2022 and its listing in the NDC Directory is set to expire on December 31, 2025 if the product is not updated or renewed by the manufacturer.

    What is the NDC billing unit for package 0409-6581-01?

    The contents of this package are billed per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.

    What is the 11-digit format for NDC 0409-6581-01?

    The 11-digit format is 00409658101. The 11-digit billing format might be required by the Centers for Medicare & Medicaid Services (CMS) and other payers in billing claim forms.

    This package code is originally configured in a 4-4-2 segment 10-digit format and by adding a zero within the original NDC package code we can obtain the converted 11-digit format in a 5-4-2 segment configuration. The table below shows the 11-digit code conversion:

    10-Digit Format10-Digit Original Code11-Digit Format11-Digit Code
    4-4-20409-6581-015-4-200409-6581-01