Isavuconazonium Sulfate Structural Formula (Image 01)
Chemical structure of isavuconazonium sulfate, the active ingredient in CRESEMBA capsules.*
Cresemba Capsule
Product Images NDC 0469-0520
8 FDA label images from Astellas Pharma Us, Inc. · Packaging, Regulatory Labels, and Product Appearance
Product Visual Gallery
This gallery contains 8 technical images submitted to the FDA as part of the official labeling for Cresemba (NDC 0469-0520). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.
As provided by Astellas Pharma Us, Inc., these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.
Product Images & Figures Index
Figure 1. The Effect Of Co-administered Drugs On Isavuconazole Exposure (Image 02)
A chart displaying the ratio and 90% confidence intervals for four drugs (Ketoconazole, Lopinavir/Ritonavir, Rifampin, and Esomeprazole) compared to Isavuconazole alone. The x-axis shows the ratio relative to Isavuconazole, with severity categories labeled as mild, moderate, and severe across the top. The chart includes measures like AUC and Cmax for each drug, illustrating their interaction levels.*
Figure 2. The Effect Of Isavuconazole On Co-administered Cyp3a4 Substrate Medications (Image 03)
A chart showing the ratio and 90% confidence intervals of various CYP3A4 substrates' pharmacokinetic parameters (AUC and Cmax) under mild and moderate conditions. Substrates include Ritonavir, Lopinavir, Prednisone, Ethinyl Estradiol, Norethindrone, Cyclosporine, Atorvastatin, Sirolimus, Midazolam, and Tacrolimus. The x-axis represents the ratio relative to substrate alone, ranging from 0 to 3.*
Figure 3. The Effect Of Isavuconazole On Exposure Of Co-administered Cyp Substrate Medications (Image 04)
A ratio and 90% confidence interval chart showing the effect of CRESEMBA (isavuconazonium sulfate) on various CYP substrate drugs. The x-axis represents the ratio relative to substrate alone, ranging from 0.0 to 3.0, classified into mild and moderate effect zones. The chart includes substrates such as caffeine, bupropion, S-methadone, R-methadone, repaglinide, S-warfarin, R-warfarin, omeprazole, and dextromethorphan, with measured parameters AUCinf and Cmax for each.*
Figure 4. The Effect Of Isavuconazole On Exposure On The Substrates Of Ugt And Transporters (Image 05)
A ratio and 90% confidence interval (CI) chart depicting the effect of a test substance on various substrates including UDP-glycosyltransferase, BCRP, OCT2, and P-gp. It shows ratios relative to substrate alone for AUCinf and Cmax of drugs like mycophenolate mofetil, methotrexate, metformin, and digoxin, with distinctions between mild and moderate impact regions.*
Cresemba (isavuconazonium Sulfate) Capsules 186 mg Blister Carton Label (Image 06)
Packaging label for Cresemba 186 mg capsules containing isavuconazonium sulfate, equivalent to 100 mg isavuconazole. The label displays dosage instructions, storage information, and manufacturer details from Astellas Pharma US, Inc. It also highlights the product as a 14-capsule unit dose blister pack for oral use, marked Rx Only.*
Image 07
Packaging label for Cresemba 372 mg (isavuconazonium sulfate) for injection, equivalent to 200 mg isavuconazole. The label indicates it is a single-dose vial for intravenous infusion only. Marketed by Astellas Pharma US, Inc., produced in Portugal. The label includes storage instructions to refrigerate at 2° to 8°C and notes the product is preservative-free, sterile, and nonpyrogenic. NDC 0469-0420-01.*
Image 08
* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.
