Estradiol Valerate Injection, Solution
Pricing Report NDC 0517-0440-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Estradiol Valerate (NDC 0517-0440-01) is $34.18321 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by American Regent, Inc., this medication is distributed in a 1 VIAL, MULTI-DOSE in 1 CARTON / 5 mL in 1 VIAL, MULTI-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$34.18321
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 VIAL, MULTI-DOSE in 1 CARTON / 5 mL in 1 VIAL, MULTI-DOSE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2020, the NADAC wholesale price for (NDC ) has moved within a range of $24.98229 to $38.63976 per ML. Over this 5 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$24.9823 - $38.6398
Market Volatility
54.67% Variance
Latest Trend
1.63%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $34.18321 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $33.63377 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $34.07500 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $34.23498 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $35.58775 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $35.05128 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $36.20560 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $36.55611 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $38.63976 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $37.32446 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $35.23714 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $33.32853 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $33.30388 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $34.47342 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $35.22632 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $33.33968 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $29.88791 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $26.04527 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $27.75415 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $24.98229 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $33.19770 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $29.20940 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $27.00580 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $29.10933 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $33.13790 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $26.40810 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $32.12510 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $36.75400 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $31.97120 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $35.36640 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $35.36640 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 18, 2023 $35.26440 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $26.35720 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $38.42360 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $33.71000 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $33.71000 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 22, 2023 $34.04618 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $36.29700 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $34.83350 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $34.04360 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $35.39440 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $36.55560 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $36.55560 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 27, 2021 $33.70342 MLC/I - Chain or Independent PharmacyCode 3, 5G - Generic
Oct 27, 2021 $33.70342 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 20, 2021 $32.22750 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 20, 2021 $32.22750 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 18, 2020 $32.36767 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $32.36767 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 23, 2020 $33.12333 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $33.12333 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 12, 2020 $30.69440 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026