Medroxyprogesterone Acetate
Pricing Report NDC 0548-5410-25
Latest NADAC: $24.86684 per ML · Effective Apr 23, 2025
Current Package Pricing Information
This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.
The latest wholesale acquisition cost for Medroxyprogesterone Acetate (NDC 0548-5410-25) is $24.86684 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Apr 23, 2025.
As a provided by Amphastar Pharmaceuticals, Inc., this medication is distributed in a 25 VIAL, SINGLE-DOSE in 1 CARTON / 1 mL in 1 VIAL, SINGLE-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $24.86684 Per ML
Pricing Unit
Effective Date
Apr 23, 2025
Data Status
As of Apr 30, 2025
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Oct 2019, the NADAC wholesale price for (NDC ) has moved within a range of $16.18729 to $42.70128 per ML. Over this 5 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$16.1873 - $42.7013
$16.1873 - $42.7013
Market Volatility
163.80% Variance
163.80% Variance
Latest Trend
7.77%
7.77%
Recent NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Apr 23, 2025 | $24.86684 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 19, 2025 | $23.07346 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 19, 2025 | $24.93787 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2025 | $21.87923 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2025 | $25.37494 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 22, 2025 | $20.50228 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 22, 2025 | $25.75309 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2024 | $20.79526 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2024 | $26.06400 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 20, 2024 | $18.65438 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 20, 2024 | $26.21440 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 23, 2024 | $24.09613 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
Earlier NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Oct 23, 2024 | $26.01269 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2024 | $23.79558 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2024 | $29.39050 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 21, 2024 | $24.39028 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 21, 2024 | $30.33007 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 17, 2024 | $16.18729 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 17, 2024 | $30.33007 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 19, 2024 | $24.46279 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 19, 2024 | $30.30330 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 22, 2024 | $16.38225 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 22, 2024 | $31.14507 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 17, 2024 | $19.02657 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 17, 2024 | $32.42147 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 20, 2024 | $26.00833 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 21, 2024 | $26.21507 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 17, 2024 | $26.30688 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 20, 2023 | $27.36629 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 22, 2023 | $27.63875 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 18, 2023 | $26.65587 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 20, 2023 | $27.61670 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 23, 2023 | $28.47971 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 19, 2023 | $27.86884 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 21, 2023 | $27.30674 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 17, 2023 | $27.70602 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 19, 2023 | $29.57243 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 22, 2023 | $27.93116 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 22, 2023 | $28.95940 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 18, 2023 | $27.86379 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 21, 2022 | $27.38778 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 23, 2022 | $29.21653 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 19, 2022 | $28.61162 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 21, 2022 | $28.82605 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 17, 2022 | $28.75096 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 20, 2022 | $31.14720 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 22, 2022 | $30.98551 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 18, 2022 | $30.26292 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 20, 2022 | $32.09225 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 23, 2022 | $31.14606 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 23, 2022 | $30.42013 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 19, 2022 | $29.15297 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 22, 2021 | $27.11552 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 17, 2021 | $31.56909 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 20, 2021 | $27.32086 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 22, 2021 | $30.12333 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 22, 2021 | $30.77229 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 22, 2021 | $30.77229 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Aug 18, 2021 | $32.71262 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 18, 2021 | $21.94544 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 21, 2021 | $29.82734 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 23, 2021 | $28.73171 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 19, 2021 | $31.99344 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 19, 2021 | $26.49296 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| May 19, 2021 | $26.49296 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Apr 21, 2021 | $31.31826 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 17, 2021 | $32.78000 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 17, 2021 | $32.83478 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 20, 2021 | $31.18446 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 20, 2021 | $27.60433 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 20, 2021 | $27.60433 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Dec 23, 2020 | $30.03779 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 18, 2020 | $33.91827 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 21, 2020 | $36.39610 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 23, 2020 | $35.22358 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Aug 19, 2020 | $37.70525 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 22, 2020 | $37.62704 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 17, 2020 | $34.81333 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 17, 2020 | $41.17914 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jun 17, 2020 | $41.17914 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| May 20, 2020 | $36.76991 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Apr 22, 2020 | $37.85573 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 18, 2020 | $39.79437 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2020 | $40.69844 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Feb 19, 2020 | $41.63916 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | G - Generic |
| Feb 19, 2020 | $41.63916 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Jan 22, 2020 | $39.92422 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jan 22, 2020 | $39.92422 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2019 | $40.70896 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Dec 18, 2019 | $40.70896 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 20, 2019 | $40.30818 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Nov 20, 2019 | $40.30818 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 23, 2019 | $42.38726 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 23, 2019 | $42.38726 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 02, 2019 | $42.70128 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Oct 02, 2019 | $42.70128 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: September 09, 2026
