Tretinoin Gel
Pricing Report NDC 0574-2301-45

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Tretinoin (NDC 0574-2301-45) is $2.27684 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Padagis Us Llc, this medication is distributed in a 1 TUBE in 1 CARTON / 45 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2.27684
Per GM

Effective Date
Jun 17, 2026
Billable Units
45 GM
Estimated Package Price
$102.46
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 TUBE in 1 CARTON / 45 g in 1 TUBE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2017, the NADAC wholesale price for (NDC ) has moved within a range of $1.49215 to $4.34162 per GM. Over this 9 years period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.1192 - $4.3416
Market Volatility
104.87% Variance
Latest Trend
1.41%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $3.45184 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $2.27684 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $3.50108 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $2.42803 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $3.33831 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $2.37012 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $3.39613 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $2.24519 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $3.43317 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $2.15875 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $3.50607 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $2.32749 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $3.42234 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $2.35507 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $3.38529 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $2.29249 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $3.34185 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $2.17141 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $3.32000 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $2.31391 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $3.46773 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $2.49925 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $3.52704 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $2.66085 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $3.51126 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $2.59198 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $3.32617 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $2.44608 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $3.24043 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $2.28379 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $3.23970 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $2.18259 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $3.16523 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $2.16241 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $2.91504 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $1.91522 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $2.87085 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $1.97212 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $2.49452 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $1.49215 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $3.14683 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $2.29242 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $2.94523 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $2.76766 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $2.38103 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $2.34423 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $2.11917 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $1.91251 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $2.51633 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $2.34778 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $2.19157 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $2.25864 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $2.78730 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $2.10679 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $3.08767 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $2.65869 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $3.38747 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $2.74049 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $3.26075 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $3.43011 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $2.87442 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $2.87442 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 18, 2023 $3.73987 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $3.73987 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 18, 2023 $2.63002 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $2.63002 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 20, 2023 $2.55857 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $3.55917 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $3.55917 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 23, 2023 $2.91489 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $3.57400 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $2.74816 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $3.35467 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $2.91533 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $3.11545 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $3.04556 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $2.57164 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $3.49653 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $3.49653 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 22, 2023 $3.10950 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $3.92908 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $2.80066 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $3.53266 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $3.53266 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 21, 2022 $2.54558 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $2.54558 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 23, 2022 $3.44282 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $2.87953 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $3.25887 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $2.84000 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $3.72211 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $3.72211 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 17, 2022 $2.75396 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $2.75396 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 20, 2022 $3.68892 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $3.91947 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $3.10428 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $3.10428 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 18, 2022 $3.93107 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $2.87453 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $3.64833 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $3.03959 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $3.65059 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $2.47886 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $3.37175 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $2.93358 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $2.92408 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $2.92408 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 18, 2021 $3.35892 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $3.35892 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 17, 2021 $3.46933 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2021 $3.46933 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 20, 2021 $3.08611 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $3.06959 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $3.06959 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 18, 2020 $2.99022 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $2.99022 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 21, 2020 $4.33267 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $3.04762 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $3.04762 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 23, 2020 $4.34162 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $3.28731 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $3.85245 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $3.17956 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $3.17956 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 17, 2020 $3.03460 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $3.01400 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $3.01400 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 18, 2020 $3.79029 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2020 $3.79029 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 18, 2019 $3.07778 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2019 $3.07778 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 20, 2019 $3.19240 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2019 $3.25663 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2019 $3.25663 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 17, 2019 $3.04460 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2019 $3.23287 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2019 $3.77480 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2019 $3.77480 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 22, 2019 $3.27124 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2019 $2.91381 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2019 $3.96225 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2019 $3.96225 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 20, 2019 $3.17656 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 20, 2019 $3.81387 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 20, 2019 $2.83422 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 19, 2018 $4.22038 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 19, 2018 $4.22038 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Dec 19, 2018 $2.74383 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 19, 2018 $2.74383 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 21, 2018 $3.99676 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2018 $2.96786 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 17, 2018 $3.09941 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 19, 2018 $3.10737 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 22, 2018 $3.98989 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 22, 2018 $3.98989 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 22, 2018 $3.17211 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 18, 2018 $3.93747 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 18, 2018 $3.18300 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 20, 2018 $3.28806 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 23, 2018 $3.07327 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 21, 2018 $3.11292 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 21, 2018 $3.11292 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 17, 2018 $4.29053 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2018 $4.29053 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 17, 2018 $3.14269 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2018 $3.14269 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 22, 2017 $3.99952 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2017 $3.99952 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Nov 22, 2017 $2.91948 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2017 $2.91948 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 20, 2017 $3.16750 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2017 $3.16750 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Sep 13, 2017 $4.08187 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 23, 2017 $3.02504 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2017 $3.20137 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 07, 2017 $3.20022 GMC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026