Promethazine Hydrochloride Injection
Pricing Report NDC 0641-0948-35

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Promethazine Hydrochloride (NDC 0641-0948-35) is $1.44016 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Hikma Pharmaceuticals Usa Inc., this medication is distributed in a 25 AMPULE in 1 CARTON / 1 mL in 1 AMPULE (0641-0948-31) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1.44016
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
25 AMPULE in 1 CARTON / 1 mL in 1 AMPULE (0641-0948-31)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2013, the NADAC wholesale price for (NDC ) has moved within a range of $0.98448 to $1.78064 per ML. Over this 12 years and 7 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.9845 - $1.7806
Market Volatility
80.87% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $1.44016 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $1.44016 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $1.44016 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $1.59648 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $1.63130 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $1.64224 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $1.65342 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $1.63874 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $1.62473 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $1.61914 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $1.61063 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $1.60491 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $1.50427 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $1.41200 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $1.38744 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $1.36287 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $1.38098 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $1.40943 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $1.47491 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $1.44823 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $1.55931 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $1.54302 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $1.57280 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $1.57280 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $1.56984 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $1.56984 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $1.78064 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $1.78064 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 19, 2016 $1.31213 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2016 $1.31213 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jun 17, 2015 $1.74013 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2015 $1.74013 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 18, 2015 $1.66360 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2015 $1.66360 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 18, 2015 $1.64360 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2015 $1.43425 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2014 $1.69872 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2014 $0.98448 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2014 $0.98448 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jul 23, 2014 $1.19867 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2014 $1.02872 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2014 $1.03764 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2014 $1.07130 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2014 $1.14171 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2014 $1.06588 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2014 $1.06440 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2013 $1.03505 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 24, 2013 $1.07535 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026