Promethazine Hydrochloride Injection
Pricing Report NDC 0641-6208-25

Current NADAC: $1.75582 per ML · Effective Aug 19, 2026
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Promethazine Hydrochloride (NDC 0641-6208-25) is $1.75582 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Hikma Pharmaceuticals Usa Inc., this medication is distributed in a 25 VIAL in 1 CARTON / 1 mL in 1 VIAL (0641-6208-01) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1.75582
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Aug 19, 2026
Data Status
As of Sep 09, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
0641-6208-25
Description
25 VIAL in 1 CARTON / 1 mL in 1 VIAL (0641-6208-01)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jul 2018, the NADAC wholesale price for (NDC ) has moved within a range of $1.02672 to $1.76912 per ML. Over this 8 years period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$1.0267 - $1.7691
Market Volatility
72.31% Variance
Latest Trend
No Change

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $1.75582 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2026 $1.75582 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $1.75407 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $1.75346 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $1.75606 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $1.76912 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $1.73213 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $1.73213 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 20, 2025 $1.73156 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $1.72946 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $1.72446 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $1.72240 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026